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Ahmed, Ayman, Elduma, Adel, Magboul, Babiker, Higazi, Tarig and Ali, Yousif (2019) 'The First Outbreak of Dengue Fever in Greater Darfur, Western Sudan.'. Tropical Medicine and Infectious Disease, Vol 4, Issue 1.
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tropicalmed-04-00043.pdf - Published Version Available under License Creative Commons Attribution. Download (1MB) | Preview |
Abstract
Dengue virus (DENV) is an arthropod-borne virus (arbovirus) transmitted by the mosquitoes, mainly . Dengue fever is a rapidly growing disease with expanding geographical distribution worldwide. We investigated a high number of non-malaria febrile cases reported to health clinics in refugee camps in the five states of Darfur between August 2015 and March 2016. The clinical presentation of cases and case definition criteria suggested involvement of one or more arboviral hemorrhagic fevers. Out of 560 suspected cases, we collected and analyzed 204 blood samples and serologically positive samples were confirmed by PCR. We identified 32 (15.7%) dengue viral infections, six West Nile virus infections, and three Crimean⁻Congo viral infections. Dengue infections were found in four out of the five Darfur states. We reported the first dengue fever outbreak in the Darfur region. Our results highlight the need for public health education and further molecular, phylogenetic, and entomological investigations for a better understanding of the disease transmission and the associated risk factors in the region.
| Item Type: | Article |
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| Subjects: | QX Parasitology > Insects. Other Parasites > QX 510 Mosquitoes QX Parasitology > Insects. Other Parasites > QX 525 Aedes WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries WC Communicable Diseases > Virus Diseases > Infectious Mononucleosis. Arbovirus Infections > WC 528 Dengue |
| Faculty: Department: | Clinical Sciences & International Health > Clinical Sciences Department |
| Digital Object Identifer (DOI): | https://doi.org/10.3390/tropicalmed4010043 |
| Depositing User: | Stacy Murtagh |
| Date Deposited: | 05 Mar 2019 10:10 |
| Last Modified: | 07 Aug 2019 15:24 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/10303 |
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