Prevalence of hypertension among patients aged 50 and older living with human immunodeficiency virus.

Dakum, Patrick, Kayode, Gbenga Ayodele, Abimiku, Alash'le, Avong, Yohanna Kambai, Okuma, James, Onyemata, Ezenwa, Ali, Taofeekat, Adekanmbi, Victor and Uthman, Olalekan (2019) 'Prevalence of hypertension among patients aged 50 and older living with human immunodeficiency virus.'. Medicine, Vol 98, Issue 15, e15024.

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Abstract

BACKGROUND
Hypertension is one of the common medical conditions observed among patients aged 50 years and elder living with HIV (EPLWH) and to date no systematic review has estimated its global prevalence.
PURPOSE
To conduct a systematic review to estimate the global prevalence of hypertension among EPLWH.
DATA SOURCES
PubMed/MEDLINE, Embase, the Cochrane Library, and Global Health databases for relevant publications up till May 25, 2018.
STUDY SELECTION
Observational studies (cohort or cross-sectional studies) that estimated the prevalence of hypertension among EPLWH.
DATA EXTRACTION
Required data were extracted independently by three reviewers and the main outcome was hypertension prevalence among EPLWH.
DATA SYNTHESIS
The 24 (n = 29,987) eligible studies included were conducted in North America, Europe, Africa, and Asia. A low level bias threat to the estimated hypertension prevalence rates was observed. The global prevalence of hypertension among EPLWH was estimated at 42.0% (95% CI 29.6%-55.4%), I = 100%. The subgroup analysis showed that North America has the highest prevalence of hypertension 50.2% (95% CI 29.2% -71.2%) followed by Europe 37.8% (95% CI 30.7%-45.7%) sub-Saharan Africa 31.9% (95% CI 18.5% -49.2%) and Asia 31.0% (95% CI 26.1%-36.3%). We found the mean age of the participants explaining a considerable part of variation in hypertension prevalence.
CONCLUSION
This study demonstrated that two out of five EPLWH are hypertensive. North America appears to have the highest prevalence of hypertension followed by Europe, sub-Saharan Africa (SSA) and Asia respectively. Findings from this study can be utilized to integrate hypertension management to HIV management package. (Registration number: CRD42018103069).

Item Type:	Article
Subjects:	WA Public Health > Statistics. Surveys > WA 900 Public health statistics WA Public Health > Statistics. Surveys > WA 950 Theory or methods of medical statistics. Epidemiologic methods WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections WG Cardiovascular System > WG 100 General works WG Cardiovascular System > WG 20 Research (General)
Faculty: Department:	Clinical Sciences & International Health > International Public Health Department
Digital Object Identifer (DOI):	https://doi.org/10.1097/MD.0000000000015024
Depositing User:	Stacy Murtagh
Date Deposited:	16 Apr 2019 11:19
Last Modified:	21 Jun 2019 14:42
URI:	https://archive.lstmed.ac.uk/id/eprint/10664

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