Adherence to antidiabetic medication and factors associated with non-adherence among patients with type-2 diabetes mellitus in two regional hospitals in Cameroon

Aminde, Leopold Ndemnge, Tindong, Maxime, Ngwasiri, Calypse A., Aminde, Jeannine A., Njim, Tsi, Fondong, Azingala Ajua and Takah, Noah Fongwen (2019) 'Adherence to antidiabetic medication and factors associated with non-adherence among patients with type-2 diabetes mellitus in two regional hospitals in Cameroon'. BMC Endocrine Disorders, Vol 19, Issue 1, e35.

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Abstract

Background
Diabetes mellitus is a growing cause of disease burden globally. Its management is multifaceted, and adherence to pharmacotherapy is known to play a significant role in glycaemic control. Data on medication adherence among affected patients is unknown in Cameroon. In this study, the level of adherence and factors influencing non-adherence to antidiabetic medication among patients with type-2 diabetes was assessed.
Methods
A hospital-based cross-sectional study among adult patients receiving care in the diabetic clinics of the Limbe and Bamenda Regional Hospitals in Cameroon was conducted. Medication adherence was assessed using the Medication Compliance Questionnaire (MCQ). Factors associated with non-adherence to medication were determined using basic and adjusted multivariable logistic regression models.

Results
A total of 195 patients with type 2 diabetes were recruited. The prevalence of non-adherence to medication was 54.4% [95% confidence interval (CI): 47.1–61.5%]. In multivariable analysis, age > 60 years (aO.R. = 0.48, 95% CI: 0.25–0.94), alcohol consumption (aO.R. = 2.13, 95% CI: 1.10–4.14) and insulin alone therapy (aO.R. = 2.85, 95% CI: 1.01–8.08) were associated with non-adherence. Patients attributed their non-adherence to forgetfulness (55.6%), lack of finances (38.2%) and disappearance of symptoms (14.2%).
Conclusions
Adherence to anti-diabetic medication is poor in this study with more than half of participants being non-adherent. Urgent interventions are required to tackle this problem in combined efforts to stem this looming diabetes epidemic.

Item Type:	Article
Subjects:	WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries WK Endocrine System > WK 810 Diabetes mellitus WK Endocrine System > WK 815 Therapy WK Endocrine System > WK 820 Insulin and its modifications
Faculty: Department:	Clinical Sciences & International Health > International Public Health Department
Digital Object Identifer (DOI):	https://doi.org/10.1186/s12902-019-0360-9
Depositing User:	Stacy Murtagh
Date Deposited:	09 May 2019 10:42
Last Modified:	23 Aug 2019 14:07
URI:	https://archive.lstmed.ac.uk/id/eprint/10768

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