Identification and Detection of a Novel Point Mutation in the Chitin Synthase Gene of Culex Pipiens Associated With Diflubenzuron Resistance

Fotakis, Emmanouil A., Mastrantonio, Valentina, Grigoraki, Linta ORCID: https://orcid.org/0000-0001-8997-0406, Porretta, Daniele, Puggioli, Arianna, Chaskopoulou, Alexandra, Osório, Hugo, Weill, Mylène, Bellini, Romeo, Urbanelli, Sandra and Vontas, John (2020) 'Identification and Detection of a Novel Point Mutation in the Chitin Synthase Gene of Culex Pipiens Associated With Diflubenzuron Resistance'. PLoS Neglected Tropical Diseases, Vol 14, Issue 5, e0008284.

Preview

Text journal.pntd.0008284_2020LG - LGrigoraki May 20.pdf - Accepted Version Available under License Creative Commons Attribution. Download (4MB) | Preview

Abstract

Diflubenzuron (DFB) is one of the most used insecticides in mosquito larval control including that of Culex pipiens, the proven vector of the recent West Nile Virus epidemics in Europe. Two mutations (I1043L and I1043M) in the chitin synthase (CHS) putative binding site of DFB have been previously reported in Cx. pipiens from Italy and associated with high levels of resistance against this larvicide.

Item Type:	Article
Subjects:	QU Biochemistry > Genetics > QU 550 Genetic techniques. PCR. Chromosome mapping QX Parasitology > Insects. Other Parasites > QX 530 Culex QX Parasitology > Insects. Other Parasites > QX 600 Insect control. Tick control
Faculty: Department:	Biological Sciences > Vector Biology Department
Digital Object Identifer (DOI):	https://doi.org/10.1371/journal.pntd.0008284
Depositing User:	Mel Finley
Date Deposited:	05 May 2020 12:52
Last Modified:	14 May 2020 09:27
URI:	https://archive.lstmed.ac.uk/id/eprint/14381

Statistics

View details

Actions (login required)

Edit Item