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Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.

O'Neill, Paul M, Amewu, Richard K, Nixon, Gemma L, Bousejra ElGarah, Fatima, Mungthin, Mathirut, Chadwick, James, Shone, Alison, Vivas, Livia, Lander, Hollie, Barton, Victoria, Muangnoicharoen, Sant, Bray, Patrick, Davies, Jill, Park, B Kevin, Wittlin, Sergio, Brun, Reto, Preschel, Michael, Zhang, Kesheng and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2010) 'Identification of a 1,2,4,5-tetraoxane antimalarial drug-development candidate (RKA 182) with superior properties to the semisynthetic artemisinins.'. Angewandte Chemie (International ed. in English), Vol 49, Issue 33, pp. 5693-7.

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Item Type: Article
Uncontrolled Keywords: antimalarial agents;drug development;endoperoxides;medicinal chemistry;tetraoxanes
Subjects: QV Pharmacology > Anti-Inflammatory Agents. Anti-Infective Agents. Antineoplastic Agents > QV 256 Antimalarials
Faculty: Department: Groups (2002 - 2012) > Molecular & Biochemical Parasitology Group
Digital Object Identifer (DOI): https://doi.org/10.1002/anie.201001026
Depositing User: Mary Creegan
Date Deposited: 17 Nov 2010 12:34
Last Modified: 17 Jul 2020 10:57
URI: https://archive.lstmed.ac.uk/id/eprint/1686

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