LSTM Home > LSTM Research > LSTM Online Archive

Summary of Guidelines for Managing Histoplasmosis among People Living with HIV

Perez, Freddy, Caceres, Diego H, Ford, Nathan, Ravasi, Giovanni, Gomez, Beatriz L, Pasqualotto, Alessandro C, Hine, Paul, Adenis, Antoine A, Nacher, Mathieu, Chiller, Tom and Badley, John (2021) 'Summary of Guidelines for Managing Histoplasmosis among People Living with HIV'. Journal Fungi, Vol 7, Issue 2, p. 134.

[img]
Preview
Text
Perez-2021-Summary-of-guidelines-for-managing-.pdf - Published Version
Available under License Creative Commons Attribution.

Download (988kB) | Preview

Abstract

Abstract: Histoplasmosis is a frequent fungal opportunistic infection in people living with HIV (PLHIV), associated every year to a total of 5% to 15% of AIDS-related deaths among this population.
In 2020, the first global guidelines for diagnosing and managing disseminated histoplasmosis among PLHIV was published. This document recommends (1) detection of circulating Histoplasma antigens as the recommended laboratory assay to diagnose histoplasmosis among PLHIV; (2) the use of liposomal amphotericin for induction therapy in severe or moderately severe disease, followed by
a maintenance therapy with itraconazole for 12 months; a shorter maintenance therapy could be considered if the patient is clinically stable and if immune status has improved; (3) antiretroviral
therapy initiation as soon as possible among patients with histoplasmosis without involvement of central nervous system; and (4) that for the treatment of co-infection with histoplasmosis and
tuberculosis (TB), treatment of TB should be initiated according to the World Health Organization treatment guidelines. Appropriate health education of providers, supportive supervision, and policy
guidance for the care of PLHIV are required.

Item Type: Article
Additional Information: This article belongs to the Special Issue Histoplasma and Histoplasmosis 2020
Subjects: WC Communicable Diseases > Mycoses > WC 465 Histoplasmosis
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections
WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503.5 Complications
WF Respiratory System > Lungs > WF 600 Lungs
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI): https://doi.org/10.3390/jof7020134
Depositing User: Christianne Esparza
Date Deposited: 22 Apr 2021 16:41
Last Modified: 22 Apr 2021 16:41
URI: https://archive.lstmed.ac.uk/id/eprint/17646

Statistics

View details

Actions (login required)

Edit Item Edit Item