WHO guidelines for plague management: revised recommendations for the use of rapid diagnostic tests, fluoroquinolones for case management and personal protective equipment for prevention of post-mortem transmission.

Jullien, Sophie, Garner, Paul ORCID: https://orcid.org/0000-0002-0607-6941 and Chaplin, Martha (2021) WHO guidelines for plague management: revised recommendations for the use of rapid diagnostic tests, fluoroquinolones for case management and personal protective equipment for prevention of post-mortem transmission. Technical Report. Geneva:.

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Abstract

Plague has killed millions of people during the past 25 centuries (1), and the disease reappeared in several countries during the 1990s. Consequently, plague was categorized as a re-emerging
disease (2). Human plague outbreaks continue to be reported, including an outbreak of pneumonic plague in Madagascar in 2017 (2–4).
Plague is an acute bacterial infection caused by Yersinia pestis. Although effective antimicrobials are available, plague still has high mortality because most outbreaks take place in remote places, where proper diagnosis and treatment remain challenging (2). Early identification of the disease is crucial to ensure prompt treatment and better outcomes. Pneumonic plague is highly contagious and of particular concern because of the high risk of triggering epidemics. Thus, plague is both a medical and a public health emergency. These guidelines were developed in accordance with the WHO handbook for guideline
development (5). A WHO Steering Group, led by the responsible technical officer, developed the draft scope of the guidelines and the key questions to be addressed. The Steering Group selected
the members of the Guideline Development Group (GDG) to ensure diverse areas of expertise were represented, including clinicians, microbiologists, public health professionals, researchers
and an anthropologist. The Steering Group also commissioned technical advisers to lead the Evidence Review Team and provide methodological support.

Item Type:	Monograph (Technical Report)
Subjects:	WA Public Health > WA 105 Epidemiology WA Public Health > Health Administration and Organization > WA 525 General works WA Public Health > Mortuary Practice > WA 840 Mortuary practice WC Communicable Diseases > WC 20 Research (General) WC Communicable Diseases > Infection. Bacterial Infections > Other Bacterial Infections. Zoonotic Bacterial Infections > WC 350 Yersinia infections. Plague
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Depositing User:	Christianne Esparza
Date Deposited:	12 Jul 2021 11:57
Last Modified:	12 Jul 2021 11:57
URI:	https://archive.lstmed.ac.uk/id/eprint/18375

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