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Sporadic cryptosporidiosis case-control study with genotyping

Hunter, P. R., Hughes, S., Woodhouse, S., Syed, Q., Verlander, N. Q., Chalmers, R. M., Morgan, K., Nichols, G., Beeching, Nicholas ORCID: https://orcid.org/0000-0002-7019-8791 and Osborn, K. (2004) 'Sporadic cryptosporidiosis case-control study with genotyping'. Emerging Infectious Diseases, Vol 10, Issue 7, pp. 1241-1249.

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Abstract

We report a case-control study of sporadic cryptosporidiosis with genotyping of isolates from case-patients. A postal questionnaire was completed by 427 patients and 427 controls. We obtained genotyping data on isolates from 191 patients; 115 were Cryptosporidium hominis, and 76 were C. parvum. When all cryptosporidiosis cases were analyzed, three variables were strongly associated with illness: travel outside the United Kingdom, contact with another person with diarrhea, and touching cattle. Eating ice cream and eating raw vegetables were both strongly negatively associated with illness. Helping a child <5 years of age to use the toilet and the number of glasses of tap water drunk at home each day were also independently positively associated with risk. Eating tomatoes was negatively associated. For C. hominis infections, the strongly significant risk factors were travel abroad and changing diapers of children <5 years of age. For C. parvum, eating raw vegetables and eating tomatoes were strongly negatively associated with illness; touching farm animals was associated with illness.

Item Type: Article
Additional Information: Suggested citation for this article: Hunter PR, Hughes S, Woodhouse S, Syed Q, Verlander NQ, Chalmers RM, et al. Sporadic cryptosporidiosis case-control study with genotyping. Emerg Infect Dis [serial on the Internet]. 2004 Jul [date cited]. Available from: http://www.cdc.gov/ncidod/EID/vol10no7/03-0582.htm
Uncontrolled Keywords: risk-factors infection water australia outbreak diarrhea
Subjects: WA Public Health > WA 100 General works
WA Public Health > Preventive Medicine > WA 108 Preventive health services. Preventive medicine. Travel Medicine.
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 730 Coccidiosis
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 765 Prevention and control
WC Communicable Diseases > Tropical and Parasitic Diseases > WC 770 Therapy
Faculty: Department: Groups (2002 - 2012) > Clinical Group
Digital Object Identifer (DOI): https://doi.org/10.3201/eid1007.030582
Depositing User: Sarah Lewis-Newton
Date Deposited: 03 Feb 2012 14:58
Last Modified: 09 Sep 2019 06:26
URI: https://archive.lstmed.ac.uk/id/eprint/2147

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