The molecular basis of insecticide resistance in mosquitoes

Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Hawkes, Nicola J., McCarroll, L. and Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247 (2004) 'The molecular basis of insecticide resistance in mosquitoes'. Insect Biochemistry and Molecular Biology, Vol 34, Issue 7, pp. 653-665.

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Abstract

Insecticide resistance is an inherited characteristic involving changes in one or more insect gene. The molecular basis of these changes are only now being fully determined, aided by the availability of the Drosophila melanogaster and Anopheles gambiae genome sequences. This paper reviews what is currently known about insecticide resistance conferred by metabolic or target site changes in mosquitoes. (C) 2004 Elsevier Ltd. All rights reserved.

Item Type:	Article
Uncontrolled Keywords:	esterase insecticide resistance molecular mechanism glutathione s-transferase (gst) gaba rdl sodium channel kdr carboxylesterase p450 monooxygenase acetylcholinesterase glutathione-s-transferase amino-acid substitution sodium-channel gene guatemalan anopheles-albimanus quinquefasciatus say diptera permethrin-impregnated nets barbital-induced expression housefly musca-domestica culex-quinquefasciatus malaria vector
Subjects:	QW Microbiology and Immunology > QW 45 Microbial drug resistance. General or not elsewhere classified. QW Microbiology and Immunology > Immune Responses > QW 700 Infection. Mechanisms of infection and resistance. QX Parasitology > Insects. Other Parasites > QX 510 Mosquitoes QX Parasitology > Insects. Other Parasites > QX 650 Insect vectors
Faculty: Department:	Groups (2002 - 2012) > Vector Group
Digital Object Identifer (DOI):	https://doi.org/10.1016/j.ibmb.2004.03.018
Depositing User:	Sarah Lewis-Newton
Date Deposited:	13 Jan 2012 15:15
Last Modified:	30 Aug 2019 17:05
URI:	https://archive.lstmed.ac.uk/id/eprint/2160

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