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Ahmed, R, Osman, N, Noory, B, Osman, R, ElHassan, H, Eltigani, H, Nightingale, Rebecca, Amaral, AFS, Patel, J, Burney, PG, Mortimer, K and El Sony, A (2023) 'Prevalence and determinants of chronic respiratory diseases in adults in Sudan'. International Journal of Tuberculosis and Lung Disease, Vol 27, Issue 5, pp. 373-380.
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Prevalence and determinants of chronic respiratory diseases in adults in Khartoum State_Final.pdf - Accepted Version Available under License Creative Commons Attribution. Download (288kB) | Preview |
Abstract
BACKGROUND:
Chronic respiratory diseases (CRDs) are considered a significant cause of morbidity and mortality worldwide, although data from Africa are limited. This study aimed to determine the prevalence and determinants of CRDs in Khartoum, Sudan.
METHODS:
Data were collected from 516 participants aged ≥40 years, who had completed a questionnaire and undertook pre- and post-bronchodilator spirometry testing. Trained field workers administered the questionnaires and conducted spirometry. Survey-weighted prevalence of respiratory symptoms and spirometric abnormalities were estimated. Regression analysis models were used to identify risk factors for chronic lung diseases.
RESULTS:
Using the Third National Health and Nutrition Examination Survey, 1988–1994 (NHANES III) reference equations, the prevalence of chronic airflow obstruction (CAO) was 10%. The main risk factor was older age, 60–69 years (OR 3.16, 95% CI 1.20–8.31). Lower education, high body mass index and a history of TB were also identified as significant risk factors. The prevalence of a low forced vital capacity (FVC) using NHANES III was 62.7% (SE 2.2) and 11.3% (SE 1.4) using locally derived values.
CONCLUSION:
The prevalence of spirometric abnormality, mainly low FVC, was high, suggesting that CRD is of substantial public health importance in urban Sudan. Strategies for the prevention and control of these problems are needed.
| Item Type: | Article |
|---|---|
| Subjects: | WF Respiratory System > WF 140 Diseases of the respiratory system (General) |
| Faculty: Department: | Clinical Sciences & International Health > Clinical Sciences Department |
| Digital Object Identifer (DOI): | https://doi.org/10.5588/ijtld.22.0462 |
| SWORD Depositor: | JISC Pubrouter |
| Depositing User: | JISC Pubrouter |
| Date Deposited: | 15 May 2023 10:52 |
| Last Modified: | 01 Nov 2023 04:12 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/22500 |
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