Malaria parasite and vector genomes: partners in crime

Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164, Kyes, S., Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247 and Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173 (2003) 'Malaria parasite and vector genomes: partners in crime'. Trends in Parasitology, Vol 19, Issue 8, pp. 356-362.

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Abstract

The publication of the genome sequences of the malaria parasite Plasmodium falciparum and the insect vector Anopheles gambiae paves the way for scientists to study these organisms by using technologies developed to observe global changes in transcription and translation, as well as computational tools. Researchers are now able to investigate complex changes involved in development, growth and reaction to external factors. Given the medical importance of these organisms, much of this work is targeted on drug or insecticide discovery (including mechanisms of resistance to existing treatments), but the genome information also provides the opportunity to develop novel therapies.

Item Type:	Article
Uncontrolled Keywords:	Plasmodium falciparum; Malaria parasite; therapies; Malaria Genome Sequencing Project
Subjects:	QU Biochemistry > Genetics > QU 470 Genetic structures QX Parasitology > Protozoa > QX 135 Plasmodia WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria
Faculty: Department:	Groups (2002 - 2012) > Molecular & Biochemical Parasitology Group Groups (2002 - 2012) > Vector Group
Digital Object Identifer (DOI):	https://doi.org/10.1016/s1471-4922(03)00146-6
Depositing User:	Ms Julia Martin
Date Deposited:	08 Sep 2011 09:17
Last Modified:	30 Aug 2019 17:05
URI:	https://archive.lstmed.ac.uk/id/eprint/2325

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