Jauneikaite, Elita, Baker, Kate S, Nunn, Jamie G, Midega, Janet T, Hsu, Li Yang, Singh, Shweta R, Halpin, Alison L, Hopkins, Katie L, Price, James R, Srikantiah, Padmini, Egyir, Beverly, Okeke, Iruka N, Holt, Kathryn E, Peacock, Sharon J and Feasey, Nicholas ORCID: https://orcid.org/0000-0003-4041-1405 (2023) 'Genomics for antimicrobial resistance surveillance to support infection prevention and control in health-care facilities'. Lancet Microbe, Vol 4, Issue 12, e1040-e1046.
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Abstract
Integration of genomic technologies into routine antimicrobial resistance (AMR) surveillance in health-care facilities has the potential to generate rapid, actionable information for patient management and inform infection prevention and control measures in near real time. However, substantial challenges limit the implementation of genomics for AMR surveillance in clinical settings. Through a workshop series and online consultation, international experts from across the AMR and pathogen genomics fields convened to review the evidence base underpinning the use of genomics for AMR surveillance in a range of settings. Here, we summarise the identified challenges and potential benefits of genomic AMR surveillance in health-care settings, and outline the recommendations of the working group to realise this potential. These recommendations include the definition of viable and cost-effective use cases for genomic AMR surveillance, strengthening training competencies (particularly in bioinformatics), and building capacity at local, national, and regional levels using hub and spoke models.
Item Type: | Article |
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Corporate Authors: | SEDRIC Genomics Surveillance Working Group |
Subjects: | QU Biochemistry > Genetics > QU 460 Genomics. Proteomics QW Microbiology and Immunology > Immune Responses > QW 700 Infection. Mechanisms of infection and resistance. |
Faculty: Department: | Clinical Sciences & International Health > Clinical Sciences Department |
Digital Object Identifer (DOI): | https://doi.org/10.1016/S2666-5247(23)00282-3 |
SWORD Depositor: | JISC Pubrouter |
Depositing User: | JISC Pubrouter |
Date Deposited: | 04 Dec 2023 16:07 |
Last Modified: | 04 Dec 2023 16:07 |
URI: | https://archive.lstmed.ac.uk/id/eprint/23602 |
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