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Mastrantonio, Valentina, Libro, Pietro, Di Martino, Jessica, Matera, Michele, Bellini, Romeo, Castrignanò, Tiziana, Urbanelli, Sandra and Porretta, Daniele (2024) 'Integrated de novo transcriptome of Culex pipiens mosquito larvae as a resource for genetic control strategies'. Scientific Data, Vol 11, Issue 1, e471.
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41597_2024_Article_3285.pdf - Published Version Available under License Creative Commons Attribution. Download (1MB) | Preview |
Abstract
We present a de novo transcriptome of the mosquito vector Culex pipiens, assembled by sequences of susceptible and insecticide resistant larvae. The high quality of the assembly was confirmed by TransRate and BUSCO. A mapping percentage until 94.8% was obtained by aligning contigs to Nr, SwissProt, and TrEMBL, with 27,281 sequences that simultaneously mapped on the three databases. A total of 14,966 ORFs were also functionally annotated by using the eggNOG database. Among them, we identified ORF sequences of the main gene families involved in insecticide resistance. Therefore, this resource stands as a valuable reference for further studies of differential gene expression as well as to identify genes of interest for genetic-based control tools.
| Item Type: | Article | ||||
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| Subjects: | QU Biochemistry > Genetics > QU 470 Genetic structures QX Parasitology > QX 20 Research (General) QX Parasitology > Insects. Other Parasites > QX 510 Mosquitoes QX Parasitology > Insects. Other Parasites > QX 530 Culex |
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| Faculty: Department: | Biological Sciences > Vector Biology Department | ||||
| Digital Object Identifer (DOI): | https://doi.org/10.1038/s41597-024-03285-1 | ||||
| SWORD Depositor: | JISC Pubrouter | ||||
| Depositing User: | JISC Pubrouter | ||||
| Date Deposited: | 16 May 2024 12:32 | ||||
| Last Modified: | 16 May 2024 12:44 | ||||
| URI: | https://archive.lstmed.ac.uk/id/eprint/24539 |
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