Geographic distribution of metabolic syndrome and its components in the general adult population: A meta-analysis of global data from 28 million individuals

Noubiap, Jean Jacques, Nansseu, Jobert Richie, Lontchi-Yimagou, Eric, Nkeck, Jan René, Nyaga, Ulrich Flore, Ngouo, Anderson T., Tounouga, Dahlia Noelle, Tianyi, Frank, Foka, Audrey Joyce, Ndoadoumgue, Aude Laetitia and Bigna, Jean Joel (2022) 'Geographic distribution of metabolic syndrome and its components in the general adult population: A meta-analysis of global data from 28 million individuals'. Diabetes Research and Clinical Practice, Vol 188, e109924.

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Abstract

Aims
Better knowledge of the global metabolic syndrome (MetS) prevalence and its components is a prerequisite to curb the related burden.

Methods
We systematically searched PubMed, EMBASE, Web of Knowledge, Africa Journal Online, Global Index Medicus up to May 23, 2021. Prevalence pooling was done with a random-effects meta-analysis.

Results
In total, 1,129 prevalence data (28,193,768 participants) were included. The MetS global prevalence varied from 12.5% (95 %CI: 10.2–15.0) to 31.4% (29.8–33.0) according to the definition considered. The prevalence was significantly higher in Eastern Mediterranean Region and Americas and increased with country’s level of income. The global prevalence was 45.1% (95 %CI: 42.1–48.2) for ethnic-specific central obesity, 42.6% (40.3–44.9) for systolic blood pressure (BP) ≥ 130 mmHg and/or diastolic BP ≥ 85 mmHg, 40.2% (37.8–42.5) for HDL-cholesterol < 1.03 for men or < 1.29 mmol/L for women, 28.9% (27.4–30.5) for serum triglycerides ≥ 1.7 mmol/L, and 24.5% (22.5–26.6) for fasting plasma glucose ≥ 5.6 mmol/L.

Conclusions
This study reveals that MetS and its related cardiometabolic components are highly prevalent worldwide. This study calls for more aggressive and contextualized public health interventions to tackle these conditions.

Item Type:	Article
Uncontrolled Keywords:	NOT_LSTM
Subjects:	QU Biochemistry > Vitamins > QU 145 Nutrition. Nutritional requirements QU Biochemistry > Vitamins > QU 146.1 General coverage WA Public Health > Statistics. Surveys > WA 900 Public health statistics
Faculty: Department:	Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI):	https://doi.org/10.1016/j.diabres.2022.109924
Depositing User:	Lynn Roberts-Maloney
Date Deposited:	16 Jul 2024 12:21
Last Modified:	16 Jul 2024 12:21
URI:	https://archive.lstmed.ac.uk/id/eprint/24935

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