Immunity to Onchocerca spp. in animal hosts

Abraham, D., Lucius, R. and Trees, Alexander J. (2002) 'Immunity to Onchocerca spp. in animal hosts'. Trends in Parasitology, Vol 18, Issue 4, pp. 164-171.

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Abstract

This review summarizes research using Onchocerca spp. in chimpanzees, cattle and mice to gain insight into the protective immune response to the filarial worm Onchocerca, volvulus in humans. In addition, Acanthocheilonema viteae has been evaluated as a surrogate filarial worm for studying immunity to the infection. Immune mechanisms controlling these infections are described and initial success using recombinant antigen vaccines in these models is reviewed.

Item Type:	Article
Subjects:	W General Medicine. Health Professions > W 20.55.V4 Veterinary biomedical research
Faculty: Department:	Groups (2002 - 2012) > Veterinary Parasitology Group (2002-2008)
Digital Object Identifer (DOI):	https://doi.org/10.1016/s1471-4922(02)02245-6
Depositing User:	Martin Chapman
Date Deposited:	14 Apr 2014 15:02
Last Modified:	06 Feb 2018 13:04
URI:	https://archive.lstmed.ac.uk/id/eprint/2887

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