Newton, P. N., Thai, L. H., Tip, N. Q., Short, J. M., Chierakul, W., Rajanuwong, A., Pitisuttithum, P., Chasombat, S., Phonrat, B., Maek-A-Nantawat, W., Teaunadi, R., Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200 and White, N. J. (2002) 'A randomized, double-blind, placebo-controlled trial of acetazolamide for the treatment of elevated intracranial pressure in cryptococcal meningitis'. Clinical Infectious Diseases, Vol 35, Issue 6, pp. 769-772.
Full text not available from this repository.Abstract
We conducted a trial of oral acetazolamide for the treatment of cryptococcal meningitis in 22 Thai adults with headache and an opening cerebrospinal fluid pressure of greater than or equal to200 mm H(2)0. The trial was terminated prematurely because patients who received acetazolamide developed significantly lower venous bicarbonate levels and higher chloride levels and had more-frequent serious adverse events than did subjects who received placebo.
Item Type: | Article |
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Subjects: | QV Pharmacology > QV 38 Drug action. WC Communicable Diseases > Infection. Bacterial Infections > Bacterial Infections > WC 245 Meningococcal infections WC Communicable Diseases > Virus Diseases > Acquired Immunodeficiency Syndrome. HIV Infections > WC 503 Acquired immunodeficiency syndrome. HIV infections WL Nervous System > WL 200 Meninges. Blood-brain barrier |
Digital Object Identifer (DOI): | https://doi.org/10.1086/342299 |
Depositing User: | Martin Chapman |
Date Deposited: | 27 Feb 2013 12:37 |
Last Modified: | 19 Nov 2024 13:47 |
URI: | https://archive.lstmed.ac.uk/id/eprint/2968 |
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