Genetic structure of Anopheles gambiae (Diptera : Culicidae) in Sao Tome and Principe (West Africa): implications for malaria control

Pinto, J., Donnelly, Martin ORCID: https://orcid.org/0000-0001-5218-1497, Sousa, C. A., Gil, V., Ferreira, C., Elissa, N., Do Rosario, V. E. and Charlwood, J. D. (2002) 'Genetic structure of Anopheles gambiae (Diptera : Culicidae) in Sao Tome and Principe (West Africa): implications for malaria control'. Molecular Ecology, Vol 11, Issue 10, pp. 2183-2187.

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Abstract

The impact of a vector eradication programme, conducted in the 1980s, on Anopheles gambiae populations from the islands of Sao Tome and Principe, was evaluated by microsatellite DNA analysis. Significant genetic differentiation was observed within and between the two islands and between the islands and a population from Gabon, suggesting a degree of isolation between them. Large estimates of long-term N-e suggested that the control programme did not affect the effective population size of the vector. Heterozygosity tests were also not consistent with a recent bottleneck.

Item Type:	Article
Subjects:	QU Biochemistry > Genetics > QU 470 Genetic structures QX Parasitology > Insects. Other Parasites > QX 515 Anopheles WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries WC Communicable Diseases > Tropical and Parasitic Diseases > WC 750 Malaria WC Communicable Diseases > Tropical and Parasitic Diseases > WC 765 Prevention and control
Digital Object Identifer (DOI):	https://doi.org/10.1046/j.1365-294X.2002.01587.x
Depositing User:	Martin Chapman
Date Deposited:	11 Jun 2013 13:51
Last Modified:	21 Nov 2024 16:06
URI:	https://archive.lstmed.ac.uk/id/eprint/2973

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