Harries, A. D., Hargreaves, N.J., Gausi, F., Kwanjana, J. H. and Salaniponi, F. M. (2001) 'High early death rate in tuberculosis patients in Malawi'. International Journal of Tuberculosis and Lung Disease, Vol 5, Issue 11, pp. 1000-1005.
Full text not available from this repository.Abstract
SETTING: Thirty-eight district and mission hospitals in Malawi.
OBJECTIVES: In patients registered with all types of tuberculosis (TB) in 1997 to determine 1) treatment outcomes, and 2) when in the course of anti-tuberculosis treatment TB deaths occurred.
DESIGN: A retrospective study using information from TB registers, health centre registers, TB treatment cards and TB ward admission books.
RESULTS: A total of 16004 patients were registered with all types of TB, 6471 with smear-positive pulmonary tuberculosis (PTB), 5305 with smear-negative PTB and 4228 with extra-pulmonary tuberculosis (EPTB). Of patients with all types of TB, 3720 (23%) died: death rates were 22% in smear-positive PTB, 26% in smear-negative PTB and 22% in EPTB. Month of death was known in 3371 patients (91% of those who died) and day of death in 3326 patients (89% of those who died). In patients who died, 19% of deaths occurred by day 7 and 41% by the end of the first month of treatment. A higher proportion of early deaths occurred in patients with smear-negative PTB and EPTB and in relation to increasing age.
CONCLUSIONS: There was a high overall death rate in TB patients registered in 1997, with 40% of deaths occurring in the first month of treatment. Strategies to combat this problem are needed.
Item Type: | Article |
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Subjects: | WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries WF Respiratory System > Tuberculosis > WF 200 Tuberculosis (General) WF Respiratory System > Tuberculosis > WF 205 Epidemiology |
Faculty: Department: | Pre 2002 |
Depositing User: | Martin Chapman |
Date Deposited: | 17 Mar 2014 12:35 |
Last Modified: | 06 Feb 2018 13:05 |
URI: | https://archive.lstmed.ac.uk/id/eprint/3155 |
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