Pregnancy and the erythrocyte sedimentation rate

Van Den Broek, Nynke ORCID: https://orcid.org/0000-0001-8523-2684 and Letsky, E. A. (2001) 'Pregnancy and the erythrocyte sedimentation rate'. British Journal of Obstetrics and Gynaecology, Vol 108, Issue 11, pp. 1164-1167.

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Abstract

Objectives To determine the range of erythrocyte sedimentation rate values obtained in healthy pregnant women. To examine the effect of gestational age and haemoglobin concentration on erythrocyte sedimentation rate. Setting Queen Charlotte's Hospital. London. UK. Design Cross sectional descriptive study. Population Health pregnant women attending for routine outpatient antenatal visit, at Queen Charlotte's Hospital in London. Methods Erythroeyte sedimentation rate was determined by the Westergren method, haemoglobin concentration by, automated cell counter and gestational age by Ultrasonography. The median and 95% reference range was determined for erythrocyte sedimentation rate Values obtained. Linear regression analysis was used to determine the influence of haemoglobin concentration and gestational age on erythrocyte sedimentation rate. Results For 1019 women examined. the range of erythrocyte sedimentation rate Values obtained was 4-112 mm/h. Gestational age and haemoglobin concentration both significantly influenced erythrocyte sedimentation rate. (P < 0.0001). For non-anaemic women the 95% reference range rose from 18-48 mm/h in the first half or pregnancy to 30-70 mm/h in the second half of pregnancy. For anaemic women the corresponding reference ranges were 21-62 mm/h and 40-95 mn/h, respectively. Conclusion For the correct interpretation of erythrocyte sedimentation rate Values obtained during pregnancy gestational age and haemoglobin concentration must he taken into account.

Item Type:	Article
Subjects:	WH Hemic and Lymphatic Systems > Hematologic Diseases. Immunologic Factors. Blood Banks > WH 150 Erythrocytes WQ Obstetrics > Pregnancy > WQ 200 General works
Faculty: Department:	Pre 2002
Digital Object Identifer (DOI):	https://doi.org/10.1016/s0306-5456(01)00267-4
Depositing User:	Martin Chapman
Date Deposited:	30 Apr 2014 13:50
Last Modified:	06 Feb 2018 13:05
URI:	https://archive.lstmed.ac.uk/id/eprint/3204

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