LSTM Home > LSTM Research > LSTM Online Archive

Front-loaded smear microscopy for the diagnosis of pulmonary TB in Tripoli, Libya.

Tools

Gammo, Mohamed, Lamaric, Widad, Hadida, Mukhtar, Abuazza, Aida, Askar, Nabil A, Yassin, Mohammed A. and Cuevas, Luis ORCID: https://orcid.org/0000-0002-6581-0587 (2013) 'Front-loaded smear microscopy for the diagnosis of pulmonary TB in Tripoli, Libya.'. Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol 107, Issue 2, pp. 137-9.

Full text not available from this repository.

Official URL: http://trstmh.oxfordjournals.org/content/107/2/137

Abstract

BACKGROUND
Diagnosis of pulmonary TB by conventional smear microscopy requires patient attendance on 2 consecutive days. We investigated whether collecting sputum on-the-spot for smear microscopy on the day the patient presented was as sensitive and specific for diagnosis as the conventional spot-morning-spot scheme.
METHOD
We enrolled 412 adults who presented between January 2009 and October 2010 at the National Centre for TB Control in Tripoli, Libya, with cough of >2 weeks' duration, into a cross-sectional survey collecting four sputum specimens: on-the-spot and Xspot on Day 1; morning and on-the-spot on Day 2.
RESULTS
97 (24%) of 401 culture results were culture positive. Spot-Xspot and spot-morning smear microscopy had, respectively, 65% and 66% sensitivity and 97% and 96% specificity (p > 0.5). Spot-Xspot-morning and Spot-morning-spot smear-microscopy had, respectively, 67% and 66% sensitivity and 96% and 96% specificity (p > 0.5).
CONCLUSION
For the diagnosis of pulmonary TB, the sensitivity and specificity of front-loaded (same-day) smear microscopy is similar to that of the standard smear microscopy scheme.

Item Type:	Article
Subjects:	QY Clinical Pathology > Diagnostic Tests > QY 120 Sputum WA Public Health > Health Problems of Special Population Groups > WA 395 Health in developing countries WF Respiratory System > Tuberculosis > WF 220 Diagnosis. Prognosis WF Respiratory System > Tuberculosis > WF 300 Pulmonary tuberculosis
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.1093/trstmh/trs023
Depositing User:	Julie Franco
Date Deposited:	15 Apr 2013 10:53
Last Modified:	17 Jul 2020 10:57
URI:	https://archive.lstmed.ac.uk/id/eprint/3356

Statistics

View details

Actions (login required)

Edit Item