Tools
Tools
Foster, Jeremy M., Hoerauf, Achim, Slatko, Barton E. and Taylor, Mark 
ORCID: https://orcid.org/0000-0003-3396-9275
(2013)
'The Wolbachia Bacterial Endosymbionts of Filarial Nematodes' in:
Kennedy, M.W. and Harnett, W., (eds)
Parasitic nematodes: molecular biology, biochemistry and immunology, Wallingford, CABI, pp. 308-336.
Abstract
This chapter discusses the symbiotic relationship between Wolbachia and filarial nematodes as indicated by antibiotic treatments and the combined analyses of the completed genomes of Wolbachia and its Brugia malayi host. Potential mechanisms that explain how Wolbachia activate innate and adaptive inflammatory responses associated with driving disease pathogenesis are described, as well as relevant molecular ligands and immunological pathways leading to disease pathogenesis.
| Item Type: | Book Section |
|---|---|
| Uncontrolled Keywords: | antibacterial agents;drug therapy;endosymbionts;endosymbiosis;filariasis;genome analysis;human diseases;immune response;immune system;immunity;inflammation;molecular genetics;pathogenesis;tetracyclines; Brugia malayi;man;Wolbachia |
| Subjects: | QU Biochemistry > Genetics > QU 550 Genetic techniques. PCR. Chromosome mapping QV Pharmacology > Anti-Bacterial Agents. Tissue Extracts > QV 350 Anti-bacterial agents (General or not elsewhere classified) QW Microbiology and Immunology > Immune Responses > QW 700 Infection. Mechanisms of infection and resistance. QX Parasitology > Helminths. Annelida > QX 301 Filarioidea |
| Faculty: Department: | Biological Sciences > Department of Tropical Disease Biology |
| Digital Object Identifer (DOI): | https://doi.org/10.1079/9781845937591.0000 |
| Related URLs: | |
| Depositing User: | Julia Martin |
| Date Deposited: | 02 Nov 2015 16:48 |
| Last Modified: | 15 Dec 2020 13:43 |
| URI: | https://archive.lstmed.ac.uk/id/eprint/4365 |
Statistics
Actions (login required)
 |
Edit Item |