Understanding organ dysfunction in Ebola virus disease

Fletcher, Tom, Fowler, Robert A. and Beeching, Nicholas ORCID: https://orcid.org/0000-0002-7019-8791 (2014) 'Understanding organ dysfunction in Ebola virus disease'. Intensive Care Medicine, Vol 40, Issue 12, pp. 1936-1939.

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Abstract

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Ebola viruses are single-stranded RNA filoviruses which are maintained in nature in fruit bats [1]. The genus includes five strains that are clinically distinguished by their usual geographic location and severity of disease in humans. The Reston strain does not appear to cause human disease, and asymptomatic human infections can also occur with other strains. The current West African outbreak is caused by the Zaire strain,which is typically associated with mortality rates of 50–90 % [2, 3]. This short review summarises knowledge about the pathogenesis of organ dysfunction in Ebola virus disease (EVD).

Item Type:	Article
Subjects:	QY Clinical Pathology > QY 4 General works WC Communicable Diseases > Virus Diseases > Viral Hemorrhagic Fevers. Other Virus Diseases > WC 534 Viral hemorrhagic fevers
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.1007/s00134-014-3515-1
Depositing User:	Julie Franco
Date Deposited:	11 Dec 2014 16:53
Last Modified:	21 Nov 2019 12:11
URI:	https://archive.lstmed.ac.uk/id/eprint/4619

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