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Identification of blaOXA-51-like, blaOXA-58, blaDIM-1, and blaVIM Carbapenemase Genes in Hospital Enterobacteriaceae Isolates from Sierra Leone

Leski, T. A., Bangura, U., Jimmy, D. H., Ansumana, R., Lizewski, S. E., Li, R. W., Stenger, D. A., Taitt, C. R. and Vora, G. J. (2013) 'Identification of blaOXA-51-like, blaOXA-58, blaDIM-1, and blaVIM Carbapenemase Genes in Hospital Enterobacteriaceae Isolates from Sierra Leone'. Journal of Clinical Microbiology, Vol 51, Issue 7, pp. 2435-2438.

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Abstract

We describe the results of a molecular epidemiological survey of 15 carbapenemase-encoding genes from a recent collection of clinical isolates from Mercy Hospital in Bo, Sierra Leone. The most salient findings revealed that (i) 60% of the isolates harbored multiple carbapenemase genes; (ii) the blaDIM-1 gene, which has previously only been reported in The Netherlands, is also circulating in this environment; and (iii) blaOXA-51-like and blaOXA-58 genes, which were thought to reside exclusively in Acinetobacter species, can also be found in members of the Enterobacteriaceae.

Item Type: Article
Subjects: QU Biochemistry > Genetics > QU 470 Genetic structures
QU Biochemistry > Genetics > QU 475 Genetic processes
QW Microbiology and Immunology > Bacteria > QW 138 Enterobacteriaceae
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI): https://doi.org/10.1128/jcm.00832-13
Depositing User: Lynn Roberts-Maloney
Date Deposited: 27 Feb 2015 11:35
Last Modified: 06 Feb 2018 13:09
URI: https://archive.lstmed.ac.uk/id/eprint/4959

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