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Agreement Between the Douleur Neuropathique in 4 Questions and Leeds Assessment of Neuropathic Symptoms and Signs Questionnaires to Classify Neuropathic Pain Among Patients with Leprosy.

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Santana, Jamilly C V, Santos, Victor S, Gurgel, Ricardo Q, Santana, Julianne C V, Reis, Francisco P, Cuevas, Luis ORCID: https://orcid.org/0000-0002-6581-0587 and Feitosa, Vera L C (2016) 'Agreement Between the Douleur Neuropathique in 4 Questions and Leeds Assessment of Neuropathic Symptoms and Signs Questionnaires to Classify Neuropathic Pain Among Patients with Leprosy.'. American Journal of Tropical Medicine and Hygiene, Vol 95, Issue 4, pp. 756-759.

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Official URL: http://www.ajtmh.org/content/95/4/756

Abstract

Neuropathic pain (NP) often occurs during the course of leprosy, and screening tools to differentiate NP from non-NP are often used. However, their performance varies in different settings. The most frequently used scales are the Douleur Neuropathique in 4 questions (DN4) and the Leeds assessment of neuropathic symptoms and signs (LANSS) questionnaires. Thus, we conducted a study to evaluate the agreement between DN4 and LANSS questionnaires to classify NP in 195 leprosy patients attending two reference centers in Sergipe, Brazil. The DN4 and LANSS classified 166 and 110 patients, respectively, as having NP. One hundred and seven (54.8%) were classified as NP by both questionnaires; 59 (30.2%) solely by the DN4 questionnaire and three (1.5%) solely by the LANSS. The agreement of the questionnaires was 66.2% (weak agreement, Kappa = 0.30). Although both questionnaires identified a high proportion of NP, the development of more robust instruments is necessary to ensure the accuracy of diagnosis of leprosy patients classified as having NP.

Item Type:	Article
Subjects:	WB Practice of Medicine > Diagnosis > General Diagnosis > WB 143 Signs and symptoms WC Communicable Diseases > Infection. Bacterial Infections > Other Bacterial Infections. Zoonotic Bacterial Infections > WC 335 Leprosy
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.4269/ajtmh.16-0366
Depositing User:	Jessica Jones
Date Deposited:	19 Sep 2016 15:19
Last Modified:	22 Nov 2018 10:47
URI:	https://archive.lstmed.ac.uk/id/eprint/6156

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