Microbe Profile: Wolbachia: a sex selector, a viral protector and a target to treat filarial nematodes

Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Bordenstein, Seth and Slatko, Barton (2018) 'Microbe Profile: Wolbachia: a sex selector, a viral protector and a target to treat filarial nematodes'. Microbiology, Vol 164, pp. 1345-1347.

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Abstract

Wolbachia is the most widespread genus of endosymbiotic bacteria in the animal world, infecting a diverse range of arthropods and nematodes. A broad spectrum of associations from parasitism to mutualism occur, with a tendency to drive reproductive manipulation or influence host fecundity to spread infection through host populations. These varied effects of Wolbachia are exploited for public health benefits. Notably, the protection of insect hosts from viruses is being tested as a potential control strategy for human arboviruses, and the mutualistic relationship with filarial nematodes makes Wolbachia a target for antibiotic therapy of human and veterinary nematode diseases.

Item Type:	Article
Subjects:	QW Microbiology and Immunology > Bacteria > QW 131 Gram-negative bacteria. QW Microbiology and Immunology > Bacteria > QW 150 Proteobacteria. Rickettsiaceae, Wolbachia WC Communicable Diseases > Tropical and Parasitic Diseases > WC 880 Filariasis and related conditions (General)
Faculty: Department:	Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI):	https://doi.org/10.1099/mic.0.000724
Depositing User:	Mary Creegan
Date Deposited:	05 Nov 2018 11:36
Last Modified:	16 Sep 2019 09:01
URI:	https://archive.lstmed.ac.uk/id/eprint/9570

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