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Nyirenda, James, Hardy, Olympia, Filho, João Da Silva, Herder, Vanessa, Attipa, Charalampos, Ndovi, Charles, Siwombo, Memory, Namalima, Takondwa Rex, Suwedi-Kapesa, Leticia, Ilia, Georgios, Nyasulu, Watipenge, Ngulube, Thokozile, Nyirenda, Deborah, Mvaya, Leonard, Phiri, Joseph, Chaswek, Dennis, Eneya, Chisomo, Makwinja, Chikondi, Phiri, Chisomo, Ziwoya, Frank, Tembo, Abel, Makwangwala, Kingsley, Khoswe, Stanley, Banda, Peter, Morton, Ben 
ORCID: https://orcid.org/0000-0002-6164-2854, Hilton, Orla, Lawrence, Sarah, Freire dos Reis, Monique, Melo, Gisely Cardoso, Guimaraes de Lacerda, Marcus Vinicius, Costa, Fabio Trindade Maranhão, Monteiro, Wuelton Marcelo, Carlos de Lima Ferreira, Luiz, Johnson, Carla, McGuinness, Dagmara, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Haley, Michael, Kumwenda, Benjamin, Palmarini, Massimo, Denno, Donna, Voskuijl, Wieger, Kamiza, Steve Bvuobvuo, Barnes, Kayla, Couper, Kevin, Marti, Matthias, Otto, Thomas and Moxon, Christopher
(2024)
'Spatially resolved single-cell atlas unveils a distinct cellular signature of fatal lung COVID-19 in a Malawian population'. Nature Medicine.
(In Press)
Doherty, Klara, Chirwa, Anthony, Songolo, Shalom, Kusakala, Alice, Nsomba, Edna, Liwonde, Pemphero, Ferreira, Daniela ORCID: https://orcid.org/0000-0002-0594-0902, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210 and Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116
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'Considerations in planning a controlled human infection model in at-risk groups in sub-Saharan Africa: the case for pneumococcal challenge in people living with HIV in Malawi and a report of stakeholder consultation'. Wellcome Open Research, Vol 9, p. 655.
(In Press)
Cocker, Derek, Birgand, Gabriel, Zhu, Nina, Rodriguez-Manzano, Jesus, Ahmad, Raheelah, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Levin, Anna S. and Holmes, Alison
(2024)
'Healthcare as a driver, reservoir and amplifier of antimicrobial resistance: opportunities for interventions'. Nature Reviews Microbiology, Vol 22, Issue 10, pp. 636-649.
Phiri, Joseph, Sibale, Lusako, Mlongoti, Lukerensia, Mitole, Ndaona, Kusakala, Alice, Khwiya, Mercy, Kayembe, Thokozani, Lisimba, Edwin, Kapwata, Prosperina, Malisita, Ken, Chaguza, Chrispin, Ferreira, Daniela ORCID: https://orcid.org/0000-0002-0594-0902, Thindwa, Deus and Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210
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'Estimating pneumococcal carriage dynamics in adults living with HIV in a mature infant pneumococcal conjugate vaccine programme in Malawi, a modelling study'. BMC Medicine, Vol 22, Issue 419.
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(2024)
'Longevity of hybrid immunity against SARS-CoV-2 in adults vaccinated with an adenovirus-based COVID-19 vaccine'. BMC Infectious Diseases, Vol 24, Issue 1, e959.
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'Challenges and Approaches to Establishing Multi-Pathogen Serosurveillance: Findings from the 2023 Serosurveillance Summit'. American Journal of Tropical Medicine and Hygiene, Vol 11, Issue 5, pp. 1145-1152.
Chikaonda, Tarsizio, Chirwa, Anthony Emeritus, Lipunga, Gareth, Thole, Faith, Galafa, Bridgette, Kamanga, Morrison Peace, Nsomba, Edna, Nkhoma, Vitumbiko S., Toto, Neema, Kudowa, Evarista, Chiwala, Gift, Dula, Dingase, Tembo, Godwin, Chimgoneko, Lorensio, Ndaferankhande, John, Makhaza, Lumbani, Ngoliwa, Clara, Banda, Ndaziona Peter Kwanjo, Henrion, Marc, Ferreira, Daniela M., Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210 and Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116
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'Experimental Human Pneumococcal Carriage using Streptococcus pneumoniae serotype 3 in Malawi: a dose ranging and reproducibility human infection study'. Wellcome Open Research, Vol 9, e467.
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'Genomic insights into the 2022–2023 Vibrio cholerae outbreak in Malawi'. Nature Communications, Vol 15, Issue 1, e6291.
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'Natural carriage of Streptococcus pneumoniae is associated with increased experimental pneumococcal carriage but reduced conjugate vaccine efficacy in a human challenge model'. Journal of Infectious Disease.
(In Press)
Tembo, G., Mayuni, M., Kamng'ona, R., Chimgoneko, L., Chiwala, G., Sichone, S., Galafa, B., Thole, F., Mkandawire, C., Chirwa, A.E., Nsomba, E., Nkhoma, V., Ngoliwa, C., Toto, N., Makhaza, L., Muyaya, A., Kudowa, E., Henrion, Marc, Dula, D., Morton, Ben ORCID: https://orcid.org/0000-0002-6164-2854, Chikaonda, T., Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116 and Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210
(2024)
'Poor association between 13-valent pneumococcal conjugate vaccine-induced serum and mucosal antibody responses with experimental Streptococcus pneumoniae serotype 6B colonisation'. Vaccine, Vol 42, Issue 12, pp. 2975-2982.
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'Low pre-existing endemic human coronavirus (HCoV-NL63)-specific T cell frequencies are associated with impaired SARS-CoV-2-specific T cell responses in people living with HIV'. Frontiers in Immunology, Vol 14, p. 1291048.
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'Experimental pneumococcal carriage in people living with HIV in Malawi: the first controlled human infection model in a key at-risk population'. Wellcome Open Research, Vol 9, Issue 2.
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'Utilizing river and wastewater as a SARS-CoV-2 surveillance tool in settings with limited formal sewage systems'. Nature Communications, Vol 14, Issue 1, e7883.
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'Acute rotavirus infection is associated with the induction of circulating memory CD4 + T cell subsets'. Scientific Reports, Vol 13, Issue 1, e9001.
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'A feasibility study of controlled human infection with Streptococcus pneumoniae in Malawi'. EBioMedicine, Vol 72, p. 103579.
Morton, Ben ORCID: https://orcid.org/0000-0002-6164-2854, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Chikaonda, Tarsizio, Rylance, Jamie ORCID: https://orcid.org/0000-0002-2323-3611, Henrion, Marc, Banda, Ndaziona Peter, Nsomba, Edna, Gondwe, Joel, Ferreira, Daniela ORCID: https://orcid.org/0000-0002-0594-0902 and Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116
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'The influence of pneumococcal conjugate vaccine-13 on nasal colonisation in a controlled human infection model of pneumococcal carriage in Malawi: a double-blinded randomised controlled trial protocol'. Wellcome Open Research, Vol 6, p. 240.
Pisu, Davide, Huang, Lu, Narang, Vipin, Theriault, Monique, Lê-Bury, Gabrielle, Lee, Bernett, Lakudzala, Agnes E, Mzinza, David T, Mhango, David V, Mitini-Nkhoma, Steven C, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Singhal, Amit, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608 and Russell, David G
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'Single cell analysis of M. tuberculosis phenotype and macrophage lineages in the infected lung'. The Journal of experimental medicine, Vol 218, Issue 9, e20210615.
Mitini-Nkhoma, Steven C, Chimbayo, Elizabeth T, Mzinza, David, Mhango, David, Chirambo, Aaron P, Mandalasi, Christine, Lakudzala, Agness E, Tembo, Dumizulu L, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210 and Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608
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'Something Old, Something New: Ion Channel Blockers as Potential Anti-Tuberculosis Agents'. Frontiers in Immunology, Vol 12, p. 665785.
Morton, Ben ORCID: https://orcid.org/0000-0002-6164-2854, Barnes, Kayla G., Anscombe, Catherine, Jere, Khuzwayo, Matambo, Prisca, Mandolo, Jonathan, Kamng’ona, Raphael, Brown, Comfort, Nyirenda, James, Phiri, Tamara, Banda, Ndaziona P., Van Der Veer, Charlotte, Mndolo, Kwazizira S., Mponda, Kelvin, Rylance, Jamie ORCID: https://orcid.org/0000-0002-2323-3611, Phiri, Chimota, Mallewa, Jane, Nyirenda, Mulinda, Katha, Grace, Kambiya, Paul, Jafali, James, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608, Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116, Phulusa, Jacob, Mkandawire, Mercy, Kaimba, Sylvester, Thole, Herbert, Nthala, Sharon, Nsomba, Edna, Keyala, Lucy, Mandala, Peter, Chinoko, Beatrice, Gmeiner, Markus, Kaudzu, Vella, Lissauer, Samantha, Freyne, Bridget, MacPherson, Peter ORCID: https://orcid.org/0000-0002-0329-9613, Swarthout, Todd, Iroh Tam, Pui-Ying ORCID: https://orcid.org/0000-0002-3682-8892, Sichone, Simon, Ahmadu, Ajisa, Kanjewa, Oscar, Nyasulu, Vita, Chinyama, End, Zuza, Allan, Denis, Brigitte, Storey, Evance, Bondera, Nedson, Matchado, Danford, Chande, Adams, Chingota, Arthur, Ntwea, Chimenya, Mkandawire, Langford, Mhango, Chimwemwe, Lakudzala, Agness, Chaponda, Mphatso, Mwenechanya, Percy, Mvaya, Leonard, Tembo, Dumizulu, Henrion, Marc, Chirombo, James, Masesa, Clemens, Gondwe, Joel, Cornick, Jennifer and Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210
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'Distinct clinical and immunological profiles of patients with evidence of SARS-CoV-2 infection in sub-Saharan Africa'. Nature Communications, Vol 12, p. 3554.
Mtunthama Toto, Neema, Gooding, Kate, Kapumba, Blessings M., Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Rylance, Jamie ORCID: https://orcid.org/0000-0002-2323-3611, Burr, Sarah, Morton, Ben ORCID: https://orcid.org/0000-0002-6164-2854, Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116 and Manda-Taylor, Lucinda
(2021)
'“At first, I was very afraid”—a qualitative description of participants’ views and experiences in the first Human Infection Study in Malawi'. Wellcome Open Research, Vol 6, p. 89.
Mhango, David V, Mzinza, David T, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210 and Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608
(2021)
'New management approaches to tuberculosis in people living with HIV'. Current Opinion in Infectious Diseases, Vol 34, Issue 1, pp. 25-33.
Kelly, Christine, Tinago, Willard, Alber, Dagmar, Hunter, Patricia, Luckhurst, Natasha, Connolly, Jake, Arrigoni, Francesca, Abner, Alejandro Garcia, Kamngona, Ralph, Sheha, Irene, Chammudzi, Mishek, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Mallewa, Jane, Rapala, Alicja, Heyderman, Robert S, Mallon, Patrick W G, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608, Walker, Sarah, Klein, Nigel and Khoo, Saye
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'Inflammatory Phenotypes Predict Changes in Arterial Stiffness Following Antiretroviral Therapy Initiation'. Clinical Infectious Diseases, Vol 71, Issue 9, pp. 2389-2397.
Gludish, David W., Boliar, Saikat, Caldwell, Shannon, Tembo, Dumizulu L., Chimbayo, Elizabeth T., Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608 and Russell, David G.
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'TZM-gfp cells: a tractable fluorescent tool for analysis of rare and early HIV-1 infection'. Scientific Reports, Vol 10, Issue 19900.
Nyazika, Tinashe, Law, Alice, Swarthout, Todd D., Sibale, Lusako, ter Braake, Danielle, French, Neil, Heyderman, Robert S., Everett, Dean, Kadioglu, Aras, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210 and Neill, Daniel R.
(2020)
'Influenza-like illness is associated with high pneumococcal carriage density in Malawian children.'. Journal of Infection, Vol 81, Issue 4, pp. 549-556.
Chibwana, Marah Grace, Jere, Khuzwayo Chidiwa, Kamng'ona, Raphael, Mandolo, Jonathan, Katunga-Phiri, Vincent, Tembo, Dumizulu, Mitole, Ndaona, Musasa, Samantha, Sichone, Simon, Lakudzala, Agness, Sibale, Lusako, Matambo, Prisca, Kadwala, Innocent, Byrne, Rachel, Mbewe, Alice, Henrion, Marc, Morton, Ben ORCID: https://orcid.org/0000-0002-6164-2854, Phiri, Chimota, Mallewa, Jane, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608, Adams, Emily ORCID: https://orcid.org/0000-0002-0816-2835, Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116 and Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210
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'High SARS-CoV-2 seroprevalence in Health Care Workers but relatively low numbers of deaths in urban Malawi.'. Wellcome Open Research, Vol 5, p. 199.
Preciado-Llanes, Lorena, Aulicino, Anna, Canals, Rocío, Moynihan, Patrick J., Zhu, Xiaojun, Jambo, Ndaru, Nyirenda, Tonney S., Kadwala, Innocent, Sousa Gerós, Ana, Owen, Siân V., Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Kumwenda, Benjamin, Veerapen, Natacha, Besra, Gurdyal S., Gordon, Melita A., Hinton, Jay C. D., Napolitani, Giorgio, Salio, Mariolina and Simmons, Alison
(2020)
'Evasion of MAIT cell recognition by the African Salmonella Typhimurium ST313 pathovar that causes invasive disease'. Proceedings of the National Academy of Sciences, Vol 117, Issue 34, pp. 20717-20728.
Nyazika, Tinashe, Kaela, Rabelani, Mugoni, Mathias, Musomekwa, Kudakwashe, Kyei-Baafour, Eric, Chiwanda, Simbarashe, Mapondera, Prichard T., Makawa, Tatenda, Sithole, Elliot M, Mavunganidze, George, Manasa, Justen, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210 and Musarurwa, Cuthbert
(2020)
'Implementation of Antibody Rapid Diagnostic Testing versus
Real-Time Reverse Transcription-PCR Sample Pooling in the
Screening of COVID-19: a Case of Different Testing Strategies
in Africa'. mSphere, Vol 5, Issue 4, e00524-20.
Morton, Ben, Burr, Sarah, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Rylance, Jamie ORCID: https://orcid.org/0000-0002-2323-3611, Henrion, Marc, Ndaziona, Banda, Nsomba, Edna, Kaumpa, Blessings, Manda Taylor, Lucinda, Masesa, Clemens, Ferreira, Daniela ORCID: https://orcid.org/0000-0002-0594-0902 and Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116
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'A pneumococcal controlled human infection model in Malawi: Transfer of an established pneumococcal carriage model from Liverpool, UK to Blantyre, Malawi – A feasibility study'. Wellcome Open Research, Vol 5, e25.
Kapumba, Blessing, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Rylance, Jamie ORCID: https://orcid.org/0000-0002-2323-3611, Gmeiner, Markus, Sambakunsi, Rodrick, Parker, Michael, Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116 and Gooding, Kate ORCID: https://orcid.org/0000-0003-4926-0287
(2020)
'Stakeholder views on the acceptability of human infection studies in Malawi'. BMC Medical Ethics, Vol 21, Issue 1.
Mitsi, Elena, Carniel, Beatriz, Reiné, Jesús, Rylance, Jamie ORCID: https://orcid.org/0000-0002-2323-3611, Zaidi, Seher, Soares-Schanoski, Alessandra, Connor, Victoria, Collins, Andrea ORCID: https://orcid.org/0000-0002-4094-1572, Schlitzer, Andreas, Nikolaou, Elissavet, SolorzanoGonzalez, Carla, Pojar, Sherin ORCID: https://orcid.org/0000-0002-7746-3279, Hill, Helen, Hyder-Wright, Angela, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Oggioni, Marco R, De Ste Croix, Megan, Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116, Jochems, Simon ORCID: https://orcid.org/0000-0002-4835-1032 and Ferreira, Daniela ORCID: https://orcid.org/0000-0002-0594-0902
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'Nasal Pneumococcal Density is Associated with Microaspiration and Heightened Human Alveolar Macrophage Responsiveness to Bacterial Pathogens.'. American Journal of Respiratory and Critical Care Medicine, Vol 201, Issue 3, pp. 335-347.
Kalata, Newton L., Nyazika, Tinashe K., Swarthout, Todd, Everett, Dean, French, Neil, Heyderman, Robert S., Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116 and Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210
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'Pneumococcal pneumonia and carriage in Africa before and after introduction of pneumococcal conjugate vaccines, 2000–2019: protocol for systematic review'. BMJ Open, Vol 9, Issue 11, e030981.
Peterson, Ingrid, Ntsui, Ntobeko, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Kelly, Christine, Huwa, Jacqueline, Afran, Louise, Tatuene, Joseph Kamtchum, Pett, Sarah, Henrion, Marc, Van Oosterhout, Joep, Heyderman, Robert S, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608 and Benjamin, Laura A
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'Evaluating the reactivation of herpesviruses and inflammation as cardiovascular and cerebrovascular risk factors in antiretroviral therapy initiators in an African HIV-infected population (RHICCA): a protocol for a longitudinal cohort study.'. BMJ Open, Vol 9, Issue 9, e025576.
Mvaya, Leonard, Mwale, Andrew, Hummel, Annemarie, Phiri, Joseph, Kamng'ona, Raphael, Mzinza, David, Chimbayo, Elizabeth, Malamba, Rose, Kankwatira, Anstead, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608 and Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210
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'Airway CD8+CD161++TCRvα7.2+ T Cell Depletion During Untreated HIV Infection Targets CD103 Expressing Cells'. Frontiers in immunology, Vol 10, p. 2003.
Kelly, Christine, Mwandumba, Henry C, Heyderman, Robert S, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Kamng’ona, Raphael, Chammudzi, Mishek, Sheha, Irene, Peterson, Ingrid, Rapala, Alicja, Mallewa, Jane, Walker, A Sarah, Klein, Nigel and Khoo, Saye
(2019)
'HIV-related arterial stiffness in Malawian adults is associated with proportion of PD-1 expressing CD8 T-cells and reverses with anti-retroviral therapy'. Journal of Infectious Disease, Vol 219, Issue 12, pp. 1948-1958.
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'Inhibition of the lncRNA SAF drives activation of apoptotic effector caspases in HIV-1-infected human macrophages.'. Proceedings of the National Academy of Sciences of the United States of America, Vol 116, Issue 15, pp. 7431-7438.
Mitsi, Elena, Kamng'ona, Raphael, Rylance, Jamie ORCID: https://orcid.org/0000-0002-2323-3611, SolorzanoGonzalez, Carla, Reiné, Jesús, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608, Ferreira, Daniela ORCID: https://orcid.org/0000-0002-0594-0902 and Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210
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'Human alveolar macrophages predominately express combined classical M1 and M2 surface markers in steady state.'. Respiratory Research, Vol 19, Issue 1, p. 66.
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'B cell, CD8 + T cell and gamma delta T cell infiltration alters alveolar immune cell homeostasis in HIV-infected Malawian adults'. Wellcome Open Research, Vol 2, p. 105.
Peno, Chikondi, Banda, Dominic H, Jambo, Ndaru, Kankwatira, Anstead M, Malamba, Rose D, Allain, Theresa J, Ferreira, Daniela ORCID: https://orcid.org/0000-0002-0594-0902, Heyderman, Robert S, Russell, David G, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608 and Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210
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'Alveolar T-helper 17 responses to streptococcus pneumoniae are preserved in ART-untreated and treated HIV-infected Malawian adults.'. Journal of Infection, Vol 76, Issue 2, pp. 168-176.
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'Heterogeneous loss of HIV transcription and proviral DNA from 8E5/LAV lymphoblastic leukemia cells revealed by RNA FISH:FLOW analyses'. Retrovirology, Vol 13, Issue 55.
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'Experimental Human Pneumococcal Carriage Augments IL-17A-dependent T-cell Defence of the Lung'. PLoS Pathogens, Vol 9, Issue 3, e1003274.
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Data Collection
Galafa, Bridgette, Howard, Ashleigh, Nyazika, Tinashe, Ferreira, Daniela ORCID: https://orcid.org/0000-0002-0594-0902, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Morton, Ben ORCID: https://orcid.org/0000-0002-6164-2854, Henrion, Marc ORCID: https://orcid.org/0000-0003-1242-839X and Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116
(2023)
Dataset for 'Natural carriage of Streptococcus pneumoniae is associated with increased experimental pneumococcal carriage but reduced conjugate vaccine efficacy in a human challenge model'.
[Data Collection]