Items where LSTM Author is "Clare, Rachel"

Article

Dawson, Charlotte ORCID: https://orcid.org/0000-0003-3922-9518, Bartlett, Keirah, Wilkinson, Mark ORCID: https://orcid.org/0000-0003-3109-6888, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Kazandjian, Taline ORCID: https://orcid.org/0000-0002-5383-0505, Hall, Steven R., Westhorpe, Adam, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Modahl, Cassandra, Harrison, Robert and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2024) 'Intraspecific venom variation in the medically important puff adder ( Bitis arietans ): Comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom'. PLoS Neglected Tropical Diseases, Vol 18, Issue 10, e0012570.

Hoffmann, Guillaume, Lukarska, Maria, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Masters, Ellen, Johnston, Kelly, Ford, Louise, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Jensen, Malene Ringkjøbing and Palencia, Andrés (2024) 'Targeting a microbiota Wolbachian aminoacyl-tRNA synthetase to block its pathogenic host.'. Science Advances, Vol 10, Issue 28, eado1453.

Solano, Gabriela, Cunningham, Sinead, Edge, Becky, Duran, Gina, Sanchez, Adriana, Villalta, Mauren, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Wilkinson, Mark ORCID: https://orcid.org/0000-0003-3109-6888, Marriott, Amy, Abada, Camille, Menzies, Stefanie ORCID: https://orcid.org/0000-0002-9273-9296, Keen, Molly, Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200, Stienstra, Ymkje, Abouyannis, Michael ORCID: https://orcid.org/0000-0003-4856-4334, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, León, Guillermo and Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482 (2024) 'African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages'. BMJ Global Health, Vol 9, Issue 3, e014813.

Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Westhorpe, Adam, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Woodley, Christopher M., James, Nivya, Kool, Jeroen, Berry, Neil G., O’Neill, Paul M. and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2024) 'Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform'. Frontiers in Pharmacology, Vol 14, p. 1331224.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Dawson, Charlotte, Westhorpe, Adam, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Woodley, Christopher M., Mosallam, Nada, Chong, Daniel J. W., Kool, Jeroen, Berry, Neil G., O’Neill, Paul M. and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2024) 'Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors'. Frontiers in Pharmacology, Vol 14, p. 1328950.

Patel, Rohit, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Ledsgaard, Line, Nys, Mieke, Kool, Jeroen, Laustsen, Andreas H, Ulens, Chris and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2023) 'An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules'. Biochemical pharmacology, Vol 216, Issue October 2023, e115758.

Menzies, Stefanie ORCID: https://orcid.org/0000-0002-9273-9296, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Xie, Chunfang, Westhorpe, Adam, Hall, Steven, Edge, Becky, Al Solaiss, Jaffer, Crittenden, Edouard, Marriott, Amy, Harrison, Robert, Kool, Jeroen and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2022) 'In vitro and in vivo preclinical venom inhibition assays identify metalloproteinase inhibiting drugs as potential future treatments for snakebite envenoming by Dispholidus typus'. Toxicon, Vol 14, p. 100118.

McGillan, Paul, Berry, Neil G., Nixon, Gemma L., Leung, Suet C., Webborn, Peter J. H., Wenlock, Mark C., Kavanagh, Stefan, Cassidy, Andrew, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Johnston, Kelly, Ford, Louise, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Hong, David and O’Neill, Paul M. (2021) 'Development of Pyrazolopyrimidine Anti-Wolbachia Agents for the Treatment of Filariasis'. ACS Medicinal Chemistry Letters, Vol 12, Issue 9, pp. 1421-1426.

Gutiérrez, José María, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Abd El-Aziz, Tarek Mohamed, Escalante, Teresa and Rucavado, Alexandra (2021) 'The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming'. Toxins, Vol 13, Issue 7, p. 451.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Hall, Steven, Patel, Rohit and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2021) 'Small molecule drug discovery for neglected tropical snakebite'. Trends in Pharmacological Sciences, Vol 42, Issue 5, pp. 340-353.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Clark, Roger, Bardelle, Catherine, Harper, Paul, Collier, Matthew, Johnston, Kelly, Plant, Helen, Plant, Darren, McCall, Eileen, Slatko, Barton E., Cantin, Lindsey, Wu, Bo, Ford, Louise, Murray, David, Rich, Kirsty, Wigglesworth, Mark, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Development of a High-Throughput Cytometric Screen to Identify Anti-Wolbachia Compounds: The Power of Public–Private Partnership'. SLAS Discovery, Vol 24, Issue 5, pp. 537-547.

Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, von Geldern, Thomas W, Ford, Louise, Hübner, Marc P, Marsh, Kennan, Johnston, Kelly, Sjoberg, Hanna, Specht, Sabine, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Tyrer, Hayley, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Murphy, Emma ORCID: https://orcid.org/0000-0001-9421-7777, Steven, Andrew, Archer, John, Bloemker, Dominique, Lenz, Franziska, Koschel, Marianne, Ehrens, Alexandra, Metuge, Haelly M, Chunda, Valerinne C, Ndongmo Chounna, Patrick W, Njouendou, Abdel J, Fombad, Fanny F, Carr, Robert, Morton, Howard E, Aljayyoussi, Ghaith, Hoerauf, Achim, Wanji, Samuel, Kempf, Dale J, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Preclinical development of an oral anti-Wolbachia macrolide drug for the treatment of lymphatic filariasis and onchocerciasis'. Science Translational Medicine, Vol 11, Issue 483.

Jacobs, Robert Toms, Lunde, Christopher S, Freund, Yvonne R, Hernandez, Vincent, Li, Xianfeng, Xia, Yi, Carter, David S, Berry, Pamela, Halladay, Jason, Rock, Fernando, Stefanakis, Rianna, Easom, Eric E, Plattner, Jacob J, Ford, Louise, Johnston, Kelly L, Cook, Darren A N, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Myhill, Laura, Tyrer, Hayley, Gamble, Joanne, Guimaraes, Ana F, Steven, Andrew, Lenz, Franziska, Ehrens, Alexandra, Frohberger, Stefan J, Koschel, Marianne, Hoerauf, Achim, Hübner, Marc P, McNamara, Case, Bakowski, Malina A, Turner, Joseph D ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark J ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Stephen A ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Boron-Pleuromutilins as Anti-Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.'. Journal of medicinal chemistry.

Hong, W David, Benayoud, Farid, Nixon, Gemma L, Ford, Louise, Johnston, Kelly, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Cook, Darren A N, Siu, Amy, Shiotani, Motohiro, Webborn, Peter J H, Kavanagh, Stefan, Aljayyoussi, Ghaith, Murphy, Emma, Steven, Andrew, Archer, John, Struever, Dominique, Frohberger, Stefan J, Ehrens, Alexandra, Hübner, Marc P, Hoerauf, Achim, Roberts, Adam ORCID: https://orcid.org/0000-0002-0760-3088, Hubbard, Alasdair ORCID: https://orcid.org/0000-0001-6668-9179, Tate, Edward W, Serwa, Remigiusz A, Leung, Suet C, Qie, Li, Berry, Neil G, Gusovsky, Fabian, Hemingway, Janet, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2019) 'AWZ1066S, a highly specific anti- drug candidate for a short-course treatment of filariasis.'. Proceedings of the National Academy of Sciences of the United States of America, Vol 116, Issue 4, pp. 1414-1419.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Bardelle, Catherine, Harper, Paul, Hong, Weiqian, Borjesson, Ulf, Johnston, Kelly, Collier, Matthew, Myhill, Laura, Cassidy, Andrew, Plant, Darren, Plant, Helen, Clark, Roger, Cook, Darren, Steven, Andrew, Archer, John, McGillan, Paul, Charoensutthivarakul, Sitthivut, Bibby, Jaclyn, Sharma, Raman, Nixon, Gemma, Slatko, Barton, Cantin, Lindsey, Wu, Bo, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ford, Louise, Rich, Kirsty, Wigglesworth, Mark, Berry, Neil, O'Neill, Paul, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2019) 'Industrial scale high-throughput screening delivers multiple fast acting macrofilaricides'. Nature Communications, Vol 10, Issue 11.

Aljayyoussi, Ghaith, Tyrer, Hayley, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Waterhouse, David, Davies, Jill, Gamble, Joanne, Metuge, Haelly, Cook, Darren, Steven, Andrew, Sharma, Raman, Guimaraes, Ana, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Johnston, Kelly, Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2018) 'Author Correction: Short-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.'. Scientific Reports, Vol 8, Issue 1, p. 1384.

Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley, Gamble, Jo, Hayward, Laura, Priestley, Richard, Murphy, Emma ORCID: https://orcid.org/0000-0001-9421-7777, Davies, Jill, Waterhouse, David, Cook, Darren, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly, Ford, Louise, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2017) 'Albendazole and antibiotics synergize to deliver short-course anti-Wolbachia curative treatments in preclinical models of filariasis'. Proceedings of the National Academy of Sciences of the United States of America, Vol 114, Issue 45, E9712-E9721.

Johnston, Kelly, Cook, Darren, Berry, Neil, Hong, Weiqian David, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Goddard, Megan, Ford, Louise, Nixon, Gemma, O'Neill, Paul, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2017) 'Identification and prioritization of novel anti-Wolbachia chemotypes from screening a 10,000-compound diversity library'. Science Advances, Vol 3, Issue 9, eaao1551.

Aljayyoussi, Ghaith, Tyrer, Hayley, Ford, Louise, Sjoberg, Hanna, Pionnier, Nicolas ORCID: https://orcid.org/0000-0002-2379-4945, Waterhouse, David, Davies, Jill, Gamble, Jo, Metugene, Haelly, Cook, Darren, Steven, Andrew, Sharma, Raman, Guimaraes, Ana, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Johnston, Kelly, Myhill, Laura, Hayward, Laura, Wanji, Samuel, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'Short Course, High Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis'. Scientific Reports, Vol 7, Issue 210.

Sharma, Raman, Aljayyoussi, Ghaith, Tyrer, Hayley, Gamble, Jo, Hayward, Laura, Guimaraes, Ana, Davies, Jill, Waterhouse, David, Cook, Darren, Myhill, Laura, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cassidy, Andrew, Steven, Andrew, Johnston, Kelly, Ford, Louise, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2016) 'Minocycline as a re-purposed anti-Wolbachia macrofilaricide: superiority compared with doxycycline regimens in a murine infection model of human lymphatic filariasis'. Scientific Reports, Vol 6, p. 23458.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Cook, Darren, Johnston, Kelly, Ford, Louise, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Taylor, Mark ORCID: https://orcid.org/0000-0003-3396-9275 (2014) 'Development and Validation of a High-Throughput Anti-Wolbachia Whole-Cell Screen: A Route to Macrofilaricidal Drugs against Onchocerciasis and Lymphatic Filariasis'. Journal of Biomolecular Screening, Vol 20, Issue 1, pp. 64-69.