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Friends or Foes? Emerging Impacts of Biological Toxins

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Clark, Graeme C, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Elliott, Christopher T, Harvey, Alan L, Jamieson, Andrew G, Strong, Peter N and Turner, Andrew D (2019) 'Friends or Foes? Emerging Impacts of Biological Toxins'. Trends in Biochemical Sciences, Vol 44, Issue 4, pp. 365-379.

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Official URL: https://www.sciencedirect.com/science/article/pii/...

Abstract

Toxins are substances produced from biological sources (e.g., animal, plants, microorganisms) that have deleterious effects on a living organism. Despite the obvious health concerns of being exposed to toxins, they are having substantial positive impacts in a number of industrial sectors. Several toxin-derived products are approved for clinical, veterinary, or agrochemical uses. This review sets out the case for toxins as 'friends' that are providing the basis of novel medicines, insecticides, and even nucleic acid sequencing technologies. We also discuss emerging toxins ('foes') that are becoming increasingly prevalent in a range of contexts through climate change and the globalisation of food supply chains and that ultimately pose a risk to health.

Item Type:	Article
Additional Information:	Contains public sector information licensed under the Open Government Licence v3.0.
Subjects:	QV Pharmacology > Toxicology > General Toxicology > QV 600 General works QW Microbiology and Immunology > Antigens and Antibodies. Toxins and Antitoxins > QW 630 Toxins. Antitoxins WA Public Health > Preventive Medicine > WA 240 Disinfection. Disinfestation. Pesticides (including diseases caused by) WA Public Health > Food > WA 695 Food. Food supply. Food inspection WD Disorders of Systemic, Metabolic or Environmental Origin, etc > Animal Poisons > WD 400 General works WD Disorders of Systemic, Metabolic or Environmental Origin, etc > Animal Poisons > WD 410 Reptiles
Faculty: Department:	Biological Sciences > Department of Tropical Disease Biology
Digital Object Identifer (DOI):	https://doi.org/10.1016/j.tibs.2018.12.004
Depositing User:	Stacy Murtagh
Date Deposited:	24 Jan 2019 12:35
Last Modified:	07 Aug 2019 15:22
URI:	https://archive.lstmed.ac.uk/id/eprint/10025

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