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Items where LSTM Author is "Albulescu, Laura-Oana"

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Number of items: 22.

Article

Abouyannis, Michael ORCID: https://orcid.org/0000-0003-4856-4334, Nyambura, Yvonne K, Ngome, Samson, Riako, Debra, Musyoki, Jennifer, Muiruri, Charles, Orindi, Benedict, Else, Laura, Amara, Alieu, Dickinson, Laura, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Westhorpe, Adam, Kool, Jeroen, Adetifa, Ifedayo, Ndungu, Francis M, FitzGerald, Richard, Khoo, Saye, Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 and Hamaluba, Mainga (2025) 'Development of an oral regimen of unithiol for the treatment of snakebite envenoming: a phase 1 open-label dose-escalation safety trial and pharmacokinetic analysis in healthy Kenyan adults.'. EBioMedicine, Vol 113, e105600.

Bartlett, Keirah, Hall, Steven, Rasmussen, Sean A., Crittenden, Edouard, Dawson, Charlotte, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Laprade, William, Harrison, Robert, Saviola, Anthony J., Modahl, Cassandra, Jenkins, Timothy P., Wilkinson, Mark ORCID: https://orcid.org/0000-0003-3109-6888, Gutiérrez, José María and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2024) 'Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib'. Proceedings of the National Academy of Sciences of the United States of America, Vol 121, Issue 19, e2315597121.

Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Westhorpe, Adam, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Woodley, Christopher M., James, Nivya, Kool, Jeroen, Berry, Neil G., O’Neill, Paul M. and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2024) 'Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform'. Frontiers in Pharmacology, Vol 14, p. 1331224.

Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Dawson, Charlotte, Westhorpe, Adam, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Woodley, Christopher M., Mosallam, Nada, Chong, Daniel J. W., Kool, Jeroen, Berry, Neil G., O’Neill, Paul M. and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2024) 'Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors'. Frontiers in Pharmacology, Vol 14, p. 1328950.

Hall, Steven, Rasmussen, Sean A., Crittenden, Edouard, Dawson, Charlotte, Bartlett, Keirah, Westhorpe, Adam, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Kool, Jeroen, Gutiérrez, José María and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2023) 'Repurposed drugs and their combinations prevent morbidity-inducing dermonecrosis caused by diverse cytotoxic snake venoms'. Nature Communications, Vol 14, Issue 1, e7812.

Alomran, Nessrin ORCID: https://orcid.org/0000-0002-9916-8182, Al Solaiss, Jaffer, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Crittenden, Edouard, Harrison, Robert, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482 and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2021) 'Pathology-specific experimental antivenoms for haemotoxic snakebite: The impact of immunogen diversity on the in vitro crossreactivity and in vivo neutralisation of geographically diverse snake venoms'. PLoS Neglected Tropical Diseases, Vol 15, Issue 8, e0009659.

Gutiérrez, José María, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Clare, Rachel ORCID: https://orcid.org/0000-0002-3945-0530, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Abd El-Aziz, Tarek Mohamed, Escalante, Teresa and Rucavado, Alexandra (2021) 'The Search for Natural and Synthetic Inhibitors That Would Complement Antivenoms as Therapeutics for Snakebite Envenoming'. Toxins, Vol 13, Issue 7, p. 451.

Kazandjian, Taline ORCID: https://orcid.org/0000-0002-5383-0505, Robinson, SD, van Thiel, J, Greene, HW, Arbuckle, K, Barlow, A, Carter, DA, Wouters, RM, Whiteley, G, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Arias, AS, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Plettenberg Laing, A, Hall, C, Heap, A, Penrhyn-Lowe, S, McCabe, CV, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482, da Silva, RR, Dorrestein, PC, Richardson, MK, Gutiérrez, JM, Calvete, JJ, Harrison, Robert, Vetter, I, Undheim, EAB, Wuster, W and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2021) 'Convergent Evolution of Pain-Inducing Defensive Venom Components in Spitting Cobras'. Science, Vol 371, Issue 6527, pp. 386-390.

Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Xie, C, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482, Al Solaiss, Jaffer, Crittenden, Edouard, Dawson, Charlotte, Softley, R, Bartlett, Keirah, Harrison, Robert, Kool, J and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2020) 'A therapeutic combination of two small molecule toxin inhibitors provides broad preclinical efficacy against viper snakebite'. Nature communications, Vol 11, Issue 6094.

Chaisakul, J, Rusmili, MRA, Al Solaiss, Jaffer, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Harrison, Robert, Othman, I and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2020) 'In Vitro Immunological Cross-Reactivity of Thai Polyvalent and Monovalent Antivenoms with Asian Viper Venoms'. Toxins, Vol 12, Issue 12, p. 766.

Xie, C, Slagboom, J, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Somsen, GW, Vonk, FJ, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 and Kool, J (2020) 'Neutralising effects of small molecule toxin inhibitors on nanofractionated coagulopathic Crotalinae snake venoms'. Acta Pharmaceutica Sinica B, Vol 10, Issue 10, pp. 1835-1845.

Xie, Chunfang, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Bittenbinder, Mátyás A, Somsen, Govert W, Vonk, Freek J, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 and Kool, Jeroen (2020) 'Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic Snake Venom Toxins.'. Biomedicines, Vol 8, Issue 9, E297.

Xie, Chunfang, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Still, Kristina B. M., Slagboom, Julien, Zhao, Yumei, Jiang, Zhengjin, Somsen, Govert W., Vonk, Freek J., Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 and Kool, Jeroen (2020) 'Varespladib Inhibits the Phospholipase A 2 and Coagulopathic Activities of Venom Components from Hemotoxic Snakes'. Biomedicines, Vol 8, Issue 6, e165.

Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Hales, MS, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482, Al Solaiss, Jaffer, Crittenden, Edouard, Calvete, Juan, Evans, Chloe, Wilkinson, Mark ORCID: https://orcid.org/0000-0003-3109-6888, Harrison, Robert, Kool, Jeroen and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2020) 'Preclinical validation of a repurposed metal chelator as an early intervention therapeutic for hemotoxic snakebite'. Science Translational Medicine, Vol 12, Issue 542, eaay8314.

Xie, C, Slagboom, J, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Bruyneel, B, Still, KBM, Vonk, FJ, Somsen, GW, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 and Kool, J (2020) 'Antivenom Neutralization of Coagulopathic Snake Venom Toxins Assessed by Bioactivity Profiling Using Nanofractionation Analytics'. Toxins, Vol 12, Issue 1, p. 53.

Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719, Petras, Daniel, Card, Darren, Suranse, Vivek, Mychajliw, Alexis, Richards, David, Koludarov, Ivan, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Slagboom, Julien, Hempel, Benjamin-Florian, Ngum, Neville, Kennerley, Rosalind, Brocca, Jorge, Whiteley, Gareth, Harrison, Robert, Bolton, Fiona, Debono, Jordan, Vonk, Freek, Alfoldi, Jessica, Johnson, Jeremy, Karlsson, Elinor, Lindblad-Toh, Kerstin, Mellor, Ian, Sussmuth, Roderich, Fry, Bryan, Kuruppu, Sanjaya, Hodgson, Wayne, Kool, Jeroen, Castoe, Todd, Barnes, Ian, Sunagar, Kartik, Undheim, Eivind and Turvey, Samuel (2019) 'Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals'. Proceedings of the National Academy of Sciences.

Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Kazandjian, Taline ORCID: https://orcid.org/0000-0002-5383-0505, Slagboom, J, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482, Alsolaiss, Jaffer, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Whiteley, Gareth, Harrison, Robert, Ulens, C, Kool, J and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2019) 'A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite'. Frontiers in Pharmacology, Vol 10, e848.

Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482, Petras, Daniel, Engmark, Mikael, Sussmuth, Roderich, Whiteley, Gareth, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Kazandijan, Taline D, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Rowley, Paul, Wüster, Wolfgang, Dorrestein, Pieter C., Arias, Ana Silvia, Gutiérrez, José M., Harrison, Robert, Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 and Calvete, Juan J (2018) 'The medical threat of mamba envenoming in sub-Saharan Africa revealed by genus-wide analysis of venom composition, toxicity and antivenomics profiling of available antivenoms.'. Journal of Proteomics, Vol 192, pp. 173-189.

Conference or Workshop Item

Hall, Steven, Crittenden, Edouard, Dawson, Charlotte, Bartlett, Keirah, Westhorpe, Adam, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217 and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2023) 'Drug combination therapies effectively inhibit the dermonecrotic activity of cytotoxic venoms from geographically diverse snake species in vivo' in British Pharmacological Society 2022, Tuesday 13th September.

Kazandjian, Taline ORCID: https://orcid.org/0000-0002-5383-0505, Petras, D, Robinson, S, Undheim, E, Arbuckle, K, Whiteley, G, Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Ainsworth, Stuart ORCID: https://orcid.org/0000-0002-0199-6482, Wagstaff, Simon ORCID: https://orcid.org/0000-0003-0577-5537, Wuster, W, Harrison, Robert, Vetter, I, Calvete, J and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2020) 'Convergent evolution of defensive venom components in spitting cobras' in 20th World Congress of the International Society on Toxinology, Buenos Aires, 8-13 September.

Albulescu, Laura-Oana ORCID: https://orcid.org/0000-0001-6563-9217, Xie, C, Hale, M, Calvete, JJ, Harrison, Robert, Kool, J and Casewell, Nicholas ORCID: https://orcid.org/0000-0002-8035-4719 (2020) 'Repurposing DMPS, a metal chelator, as a rapid field intervention for treating hemotoxic snakebite' in 20th World Congress of the International Society on Toxinology, Buenos Aires, 8-13 September.

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