Items where LSTM Author is "Biagini, Giancarlo"

Article

Clark, Jordan J., Penrice-Randal, Rebekah, Sharma, Parul, Dong, Xiaofeng, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Marriott, Amy, Colombo, Stefano, Davidson, Andrew, Kavanagh Williamson, Maia, Matthews, David A., Turtle, Lance, Prince, Tessa, Hughes, Grant ORCID: https://orcid.org/0000-0002-7567-7185, Patterson, Ian ORCID: https://orcid.org/0000-0003-3465-0848, Shawli, Ghada, Mega, Daniele F., Subramaniam, Krishanthi, Sharp, Jo, Turner, Joseph ORCID: https://orcid.org/0000-0002-2185-5476, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Owen, Andrew, Kipar, Anja, Hiscox, Julian A. and Stewart, James P. (2024) 'Sequential Infection with Influenza A Virus Followed by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Leads to More Severe Disease and Encephalitis in a Mouse Model of COVID-19'. Viruses, Vol 16, Issue 6, e863.

Box, Helen J, Sharp, Joanne, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Kijak, Edyta, Tatham, Lee, Caygill, Claire H, Lopeman, Rose, Jeffreys, Laura ORCID: https://orcid.org/0000-0002-0607-6116, Herriott, Joanne, Neary, Megan, Valentijn, Anthony, Pertinez, Henry, Curley, Paul, Arshad, Usman, Rajoli, Rajith K R, Jochmans, Dirk, Vangeel, Laura, Neyts, Johan, Chatelain, Eric, Escudié, Fanny, Scandale, Ivan, Rannard, Steve, Stewart, James P, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Owen, Andrew (2023) 'Lack of antiviral activity of probenecid in vitro and in Syrian golden hamsters'. Journal of Antimicrobial Chemotherapy, Vol 79, Issue 1, pp. 172-178.

Carter, Emma, Morton, Ben ORCID: https://orcid.org/0000-0002-6164-2854, ElSafadi, Dima, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Kenny-Nyazika, Tinashe, Hyder-Wright, Angela, Chiwala, Gift, Chikaonda, Tarsizio, Chirwa, Anthony, Gonzalez-Sanchez, Jonathan, Yip, Vincent, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Saunderson, Paula, Farrar, Madlen, Myerscough, Christopher, Collins, Andrea ORCID: https://orcid.org/0000-0002-4094-1572, Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116 and Ferreira, Daniela ORCID: https://orcid.org/0000-0002-0594-0902 (2023) 'A feasibility study of controlled human infection with intradermal Bacillus Calmette–Guérin (BCG) injection: Pilot BCG controlled human infection model'. Wellcome Open Research, Vol 8, e424.

Collings, Kieran, Boisdon, Cedric, Sham, Tung-Ting, Skinley, Kevin, Oh, Hyun-Kyung, Prince, Tessa, Ahmed, Adham, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Brownridge, Philip J., Edwards, Thomas, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Eyers, Claire E., Lamb, Amanda, Myers, Peter and Maher, Simon (2023) 'Attaching protein-adsorbing silica particles to the surface of cotton substrates for bioaerosol capture including SARS-CoV-2'. Nature Communications, Vol 14, Issue 1, e5033.

Neary, Megan, Arshad, Usman, Tatham, Lee, Pertinez, Henry, Box, Helen, Rajoli, Rajith K R, Valentijn, Anthony, Sharp, Joanne, Rannard, Steve P, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Curley, Paul and Owen, Andrew (2023) 'Quantitation of tizoxanide in multiple matrices to support cell culture, animal and human research'. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, Vol 1228, e123823.

Jeffreys, Laura ORCID: https://orcid.org/0000-0002-0607-6116, Ardrey, Alison, Hafiz, Taghreed, Dyer, Lauri-Anne, Warman, Ashley, Mosallam, Nada, Nixon, Gemma, Fisher, Nicholas, Hong, W. David, Leung, Suet C., Aljayyoussi, Ghaith, Bibby, Jaclyn, Almeida, Deepak V., Converse, Paul J., Fotouhi, Nader, Berry, Neil G., Nuermberger, Eric L., Upton, Anna M., O’Neill, Paul M., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2023) 'Identification of 2-Aryl-Quinolone Inhibitors of Cytochrome bd and Chemical Validation of Combination Strategies for Respiratory Inhibitors against Mycobacterium tuberculosis'. ACS Infectious Diseases, Vol 9, Issue 2, pp. 221-238.

Gordon, Stephen ORCID: https://orcid.org/0000-0001-6576-1116, Sichone, Simon, Chirwa, Anthony E., Hazenberg, Phoebe, Kafuko, Zacharia, Ferreira, Daniela ORCID: https://orcid.org/0000-0002-0594-0902, Flynn, Joanne, Fortune, Sarah, Balasingam, Shobana, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, McShane, Helen, Mwandumba, Henry ORCID: https://orcid.org/0000-0003-4470-3608, Jambo, Kondwani ORCID: https://orcid.org/0000-0002-3195-2210, Dedha, Keertan, Raj Sharma, Nimisha, Robertson, Brian D., Walker, Naomi ORCID: https://orcid.org/0000-0002-3345-7694 and Morton, Ben ORCID: https://orcid.org/0000-0002-6164-2854 (2023) 'Practical considerations for a TB controlled human infection model (TB-CHIM); the case for TB-CHIM in Africa, a systematic review of the literature and report of 2 workshop discussions in UK and Malawi'. Wellcome Open Research, Vol 8, p. 71.

Donnellan, Samantha, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Ruggiero, Alessandra, Martinez-Rodriguez, Carmen, Pouget, Marion, Thomas, Jordan, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Pollakis, Georgios, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Paxton, William (2022) 'A quantitative method for the study of HIV-1 and Mycobacterium tuberculosis co-infection'. Journal of Infectious Disease, Vol 227, Issue 5, pp. 708-713.

Amporndanai, Kangsa, Pinthong, Nattapon, O’Neill, Paul M., Hong, W. David, Amewu, Richard K., Pidathala, Chandrakala, Berry, Neil G., Leung, Suet C., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Hasnain, S. Samar and Antonyuk, Svetlana V. (2022) 'Targeting the Ubiquinol-Reduction (Qi) Site of the Mitochondrial Cytochrome bc1 Complex for the Development of Next Generation Quinolone Antimalarials'. Biology, Vol 11, Issue 8, e1109.

Jeffreys, Laura ORCID: https://orcid.org/0000-0002-0607-6116, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Duggan, Jack, Caygill, Claire, Lopeman, Rose, Breen, Alastair, Jinks, Jessica, Ardrey, Alison, Donnellan, Samantha, Patterson, Ian ORCID: https://orcid.org/0000-0003-3465-0848, Hughes, Grant ORCID: https://orcid.org/0000-0002-7567-7185, Hong, David W, O'Neill, Paul M, Aljayyoussi, Ghaith, Owen, Andrew, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2022) 'Remdesivir-ivermectin combination displays synergistic interaction with improved in vitro activity against SARS-CoV-2'. International Journal of Antimicrobial Agents, Vol 59, Issue 3, e106542.

Djidrovksi, Ivo, Georgiou, Maria, Hughes, Grant ORCID: https://orcid.org/0000-0002-7567-7185, Patterson, Ian ORCID: https://orcid.org/0000-0003-3465-0848, Casas Sanchez, Aitor ORCID: https://orcid.org/0000-0001-5237-1223, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Moya-Molina, Marina, van den Bo, Jelle, Smit, Martine J., Chung, Git and Lako, Majlinda (2021) 'SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells'. Stem Cells, Vol 39, Issue 10, pp. 1310-1321.

Woodley, Christopher M., Nixon, Gemma L., Basilico, Nicoletta, Parapini, Silvia, Hong, Weiqian David, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Leung, Suet C., Taramelli, Donatella, Onuma, Keiko, Hasebe, Takashi and O’Neill, Paul M. (2021) 'Enantioselective Synthesis and Profiling of Potent, Nonlinear Analogues of Antimalarial Tetraoxanes E209 and N205'. ACS Medicinal Chemistry Letters, Vol 12, Issue 7, pp. 1077-1085.

Donnellan, Samantha, Martínez-Rodríguez, Carmen, Aljayyoussi, Ghaith and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2021) 'Measurement of the Intracellular Mycobacterium tuberculosis Drug Effect and Prediction of the Clinical Dose–Response Relationship Using Intracellular Pharmacodynamic Modeling (PDi)'. Methods in Molecular Biology, Vol 2296, pp. 393-408.

Stachulski, Andrew V., Taujanskas, Joshua, Pate, Sophie L., Rajoli, Rajith K. R., Aljayyoussi, Ghaith, Pennington, Shaun H. ORCID: https://orcid.org/0000-0002-7160-6275, Ward, Stephen A. ORCID: https://orcid.org/0000-0003-2331-3192, Hong, Weiqian David, Biagini, Giancarlo A. ORCID: https://orcid.org/0000-0001-6356-6595, Owen, Andrew, Nixon, Gemma L., Leung, Suet C. and O’Neill, Paul M. (2021) 'Therapeutic Potential of Nitazoxanide: An Appropriate Choice for Repurposing versus SARS-CoV-2?'. ACS Infectious Diseases, Vol 7, Issue 6, pp. 1317-1331.

Rajoli, Rajith K.R., Pertinez, Henry, Arshad, Usman, Box, Helen, Tatham, Lee, Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J., Valentijn, Anthony, David, Christopher, Rannard, Steven P., Aljayyoussi, Ghaith, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Hill, Andrew, Boffito, Marta, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Khoo, Saye, Bray, Patrick G., O'Neill, Paul M., Hong, W. David, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Owen, Andrew (2021) 'Dose Prediction for Repurposing Nitazoxanide in SARS‐CoV‐2 Treatment or Chemoprophylaxis'. British Journal of Clinical Pharmacology, Vol 87, Issue 4, pp. 2078-2088.

Arshad, Usman, Pertinez, Henry, Box, Helen, Tatham, Lee, Rajoli, Rajith KR, Curley, Paul, Neary, Megan, Sharp, Joanne, Liptrott, Neill J, Valentijn, Anthony, David, Christopher, Rannard, Steve P, O’Neill, Paul M, Aljayyoussi, Ghaith, Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Hill, Andrew, Back, David J, Khoo, Saye H, Bray, Patrick G, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Owen, Andrew (2020) 'Prioritisation of Anti‐SARS‐Cov‐2 Drug Repurposing Opportunities Based on Plasma and Target Site Concentrations Derived from their Established Human Pharmacokinetics'. Clinical Pharmacology and Therapeutics, Vol 108, Issue 4, pp. 775-790.

Fisher, Nicholas, Meunier, Brigitte and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2020) 'The cytochrome bc1 complex as an antipathogenic target'. Febs Letters, Vol 594, Issue 18, pp. 2935-2952.

McPhillie, Martin, Zhou, Ying, Hickman, Mark, Gordon, James, Weber, Christopher R., Li, Qigui, Lee, Patty, Amporndana, Kangsa, Johnson, Rachel, Darby, Heather, Woods, Stuart, Li, Zhuhong, Priestley, Richard, Ristroph, Kurt, Biering, Scott B, EL BISSATI, KAMAL, Hwang, Seungmin, Hakim, Farida E., Dovgin, Sarah D, Lykins, Joseph D., Roberts, Lucy, Hargrave, Kerrie, Cong, Hua, Sinai, Anthony P., Muench, Stephen P., Dube, Jitender, Prud'homme, Robert, Lorenzi, Hernan A., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Moreno, Silvia N., Roberts, Craig W., Atonyuk, Svetlana, Fishwick, Colin and McLeod, Rima (2020) 'Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites'. Frontiers in Cellular and Infection Microbiology, Vol 10, p. 203.

Ullah, Imran, Sharma, Raman, Mete, Antonio, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Wetzel, Dawn M. and Horrocks, Paul D. (2020) 'The relative rate of kill of the MMV Malaria Box compounds provide links to the mode of antimalarial action and highlight scaffolds of medicinal chemistry interest'. Journal of Antimicrobial Chemotherapy, Vol 75, Issue 2, pp. 362-370.

Jin, Celina, Gibani, Malick M, Pennington, Shaun. H ORCID: https://orcid.org/0000-0002-7160-6275, Liu, Xinxue, Ardrey, Alison, Aljayyoussi, Ghaith, Moore, Maria, Angus, Brian, Parry, Christopher, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Feasey, Nicholas ORCID: https://orcid.org/0000-0003-4041-1405 and Pollard, Andrew J (2019) 'Treatment responses to Azithromycin and Ciprofloxacin in uncomplicated Salmonella Typhi infection: A comparison of Clinical and Microbiological Data from a Controlled Human Infection Model'. PLoS Neglected Tropical Diseases, Vol 13, Issue 12, e0007955.

Donnellan, Samantha, Aljayyoussi, Ghaith, Moyo, Emmanuel, Ardrey, Alison, Martinez-Rodriguez, Carmen, Ward, Stephen A ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo A ORCID: https://orcid.org/0000-0001-6356-6595 (2019) 'Intracellular pharmacodynamic modelling (PDi) is predictive of the clinical activity of fluoroquinolones against Tuberculosis'. Antimicrobial Agents and Chemotherapy, Vol 64, e00989-19.

Camarda, Grazia, Jirawatcharadech, Piyaporn, Priestley, Richard, Saif, Ahmed, March, Sandra, Wong, Michael H. L., Leung, Suet, Miller, Alex, Baker, David A., Alano, Pietro, Paine, Mark ORCID: https://orcid.org/0000-0003-2061-7713, Bhatia, Sangeeta N., O'Neill, Paul M., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2019) 'Antimalarial activity of primaquine operates via a two-step biochemical relay'. Nature Communications, Vol 10, p. 3226.

Aljayyoussi, Ghaith, Donnellan, Samantha, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2019) 'Intracellular PD Modelling (PDi) for the Prediction of Clinical Activity of Increased Rifampicin Dosing'. Pharmaceutics, Vol 11, Issue 6, p. 278.

Hong, David, Leung, S, Amporndanai, Kangsa, Davies, Jill, Priestley, Richard, Nixon, Gemma L., Berry, Neil G., Samar Hasnain, S., Antonyuk, Svetlana, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and O’Neill, Paul M. (2018) 'Potent Antimalarial 2-Pyrazolyl Quinolone bc1 (Qi) Inhibitors with Improved Drug-like Properties'. ACS Medicinal Chemistry Letters, Vol 9, Issue 12, pp. 1205-1210.

O' Neill, Paul M, Stocks, Paul A, Sabbani, Sunil, Roberts, Natalie L, Amewu, Richard K, Shore, Emma R, Aljayyoussi, Ghaith, Angulo-Barturén, Iñigo, Belén, María, Díaz, Jiménez, Bazaga, Santiago Ferrer, Martínez, María Santos, Campo, Brice, Sharma, Raman, Charman, Susan A, Ryan, Eileen, Chen, Gong, Shackleford, David M, Davies, Jill, Nixon, Gemma L, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2018) 'Synthesis and profiling of benzylmorpholine 1,2,4,5-tetraoxane analogue N205: Towards tetraoxane scaffolds with potential for single dose cure of malaria.'. Bioorganic and Medicinal Chemistry, Vol 26, Issue 11, pp. 2996-3005.

O'Neill, Paul M, Amewu, Richard K, Charman, Susan A, Sabbani, Sunil, Gnädig, Nina F, Straimer, Judith, Fidock, David A, Shore, Emma R, Roberts, Natalie L, Wong, Michael H-L, Hong, W David, Pidathala, Chandrakala, Riley, Chris, Murphy, Ben, Aljayyoussi, Ghaith, Gamo, Francisco Javier, Sanz, Laura, Rodrigues, Janneth, Cortes, Carolina Gonzalez, Herreros, Esperanza, Angulo-Barturén, Iñigo, Jiménez-Díaz, María Belén, Bazaga, Santiago Ferrer, Martínez-Martínez, María Santos, Campo, Brice, Sharma, Raman, Ryan, Eileen, Shackleford, David M, Campbell, Simon, Smith, Dennis A, Wirjanata, Grennady, Noviyanti, Rintis, Price, Ric N, Marfurt, Jutta, Palmer, Michael J, Copple, Ian M, Mercer, Amy E, Ruecker, Andrea, Delves, Michael J, Sinden, Robert E, Siegl, Peter, Davies, Jill, Rochford, Rosemary, Kocken, Clemens H M, Zeeman, Anne-Marie, Nixon, Gemma L, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance.'. Nature Communications, Vol 8, e15159.

Hong, David, Gibbons, Peter, Leung, Suet C, Amewu, Richard, Stocks, Paul A, Stachulski, Andrew, Horta, Pedro, Cristiano, Maria L. S., Shone, Alison, Moss, Darren, Ardrey, Alison, Sharma, Raman, Warman, Ashley, Bedingfield, Paul, Fisher, Nicholas, Aljayyoussi, Ghaith, Mead, Sally, Caws, Maxine ORCID: https://orcid.org/0000-0002-9109-350X, Berry, Neil, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, O’Neill, Paul M and Nixon, Gemma L (2017) 'Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis'. Journal of Medicinal Chemistry, Vol 60, Issue 9, pp. 3703-3726.

Aljayyoussi, Ghaith, Jenkins, Victoria, Sharma, Raman, Donnellan, Samantha, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2017) 'Pharmacokinetic-Pharmacodynamic modelling of intracellular Mycobacterium tuberculosis growth and kill rates is predictive of clinical treatment duration'. Scientific Reports, Vol 7, Issue 502.

Ullah, Imran, Sharma, Raman, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Horrocks, Paul (2017) 'A validated bioluminescence-based assay for the rapid determination of the initial rate of kill for discovery antimalarials'. Journal of Antimicrobial Chemotherapy, Vol 72, Issue 3, pp. 717-726.

Aljayyoussi, Ghaith, Kay, Katherine, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2016) 'OptiMal-PK: an internet-based, user-friendly interface for the mathematical-based design of optimized anti-malarial treatment regimens.'. Malaria Journal, Vol 15, Issue 344.

Ismail, Hanafy ORCID: https://orcid.org/0000-0002-9953-9588, Barton, Victoria E., Panchana, Matthew, Charoensutthivarakul, Sitthivut, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M. (2016) 'A Click Chemistry-Based Proteomic Approach Reveals that 1,2,4-Trioxolane and Artemisinin Antimalarials Share a Common Protein Alkylation Profile'. Angewandte Chemie International Edition, Vol 128, Issue 22, pp. 6401-6405.

Ismail, Hanafy ORCID: https://orcid.org/0000-0002-9953-9588, Barton, Victoria, Phanchana, Matthew, Charoensutthivarakul, Sitthivut, Wong, Michael H L, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, O’Neill, Paul M and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2016) 'Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasites Plasmodium falciparum 3D7'. Proceedings of the National Academy of Sciences, Vol 113, Issue 8, pp. 2080-2085.

McConville, Matthew, Fernández, Jorge, Angulo-Barturen, Íñigo, Bahamontes-Rosa, Noemi, Ballell-Pages, Lluis, Castañeda, Pablo, de Cózar, Cristina, Crespo, Benigno, Guijarro, Laura, Jiménez-Díaz, María Belén, Martínez-Martínez, Maria S, de Mercado, Jaime, Santos-Villarejo, Ángel, Sanz, Laura M, Frigerio, Micol, Washbourn, Gina, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Nixon, Gemma L, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Berry, Neil G, Blackman, Michael J, Calderón, Félix and O'Neill, Paul M (2015) 'Carbamoyl Triazoles, Known Serine Protease Inhibitors, Are a Potent New Class of Antimalarials.'. Journal of medicinal chemistry, Vol 58, Issue 16, pp. 6448-6455.

Charoensutthivarakul, Sitthivut, David Hong, W., Leung, Suet C., Gibbons, Peter D., Bedingfield, Paul, Nixon, Gemma L., Lawrenson, Alexandre S., Berry, Neil G., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and O'Neill, Paul (2015) '2-Pyridylquinolone antimalarials with improved antimalarial activity and physicochemical properties'. MedChemComm, Vol 6, Issue 7, pp. 1252-1259.

Capper, Michael J., O’Neill, Paul M., Fisher, Nicholas, Strange, Richard W., Moss, Darren M., Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Berry, Neil G., Lawrenson, Alexandre S., Hasnain, S. Samar, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Antonyuk, Svetlana V. (2015) 'Antimalarial 4(1H)-pyridones bind to the Qisite of cytochromebc1'. Proceedings of the National Academy of Sciences, Vol 112, Issue 3, pp. 755-760.

Antoine, Thomas, Fisher, Nicholas, Amewu, R., O'Neill, P. M., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2014) 'Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential'. Journal of Antimicrobial Chemotherapy, Vol 69, Issue 4, pp. 1005-1016.

Salcedo, Enrique, Caamno-Gutierrez, Eva, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2014) 'The proliferating cell hypothesis: a metabolic framework for Plasmodium growth and development'. Trends in Parasitology, Vol 30, Issue 4, pp. 170-175.

Stocks, P.A., Barton, V., Antoine, T., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, P. M. (2014) 'Novel inhibitors of the Plasmodium falciparum electron transport chain'. Parasitology, Vol 141, Issue 1, pp. 50-65.

Ressurreição, Ana S, Gonçalves, Daniel, Sitoe, Ana R, Albuquerque, Inês S, Gut, Jiri, Góis, Ana, Gonçalves, Lídia M, Bronze, Maria R, Hanscheid, Thomas, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Rosenthal, Philip J, Prudêncio, Miguel, O'Neill, Paul, Mota, Maria M, Lopes, Francisca and Moreira, Rui (2013) 'Structural optimization of quinolon-4(1H)-imines as dual-stage antimalarials: toward increased potency and metabolic stability.'. Journal of Medicinal Chemistry, Vol 56, Issue 19, pp. 7679-7690.

Nixon, Gemma, Pidathala, Chandrakala, Shone, Alison E, Antoine, Thomas, Fisher, Nicholas, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2013) 'Targeting the mitochondrial electron transport chain of Plasmodium falciparum: new strategies towards the development of improved antimalarials for the elimination era.'. Future medicinal chemistry, Vol 5, Issue 13, pp. 1573-1591.

Nixon, Gemma, Moss, Darren M., Shone, Alison, Lalloo, David ORCID: https://orcid.org/0000-0001-7680-2200, Fisher, Nicholas, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2013) 'Antimalarial pharmacology and therapeutics of atovaquone.'. The Journal of Antimicrobial Chemotherapy, Vol 68, Issue 5, pp. 977-985.

Warman, Ashley, Rito, Teresa S, Fisher, Nicholas, Moss, Darren M., Berry, Neil G, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2013) 'Antitubercular pharmacodynamics of phenothiazines'. Journal of Antimicrobial Chemotherapy, Vol 68, Issue 4, pp. 869-880.

van Schalkwyk, Donelly A., Saliba, Kevin J., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick and Kirk, Kiaran (2013) 'Loss of pH control in Plasmodium falciparum parasites subjected to oxidative stress'. PLoS ONE, Vol 8, Issue 3, e58933.

Salcedo, Enrique, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2012) 'A yeast expression system for functional and pharmacological studies of the malaria parasite Ca2+/H+ antiporter.'. Malaria Journal, Vol 11, p. 254.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fisher, Nicholas, Shone, Alison, Mubaraki, Murad A., Srivastava, Abhishek, Hill, Alasdair, Antoine, Thomas, Warman, Ashley, Davies, Jill, Pidathala, Chandrakala, Amewu, Richard K, Leung, Suet C, Sharma, Raman, Gibbons, Peter, Hong, David W, Pacorel, Bénédicte, Lawrenson, Alexandre S, Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Stocks, Paul A., Nixon, Gemma, Chadwick, James, Hemingway, Janet ORCID: https://orcid.org/0000-0002-3200-7173, Delves, Michael J, Sinden, Robert E, Zeeman, Anne-Marie, Kocken, Clemens H M, Berry, Neil G, O'Neill, Paul M and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2012) 'Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria.'. Proceedings of the National Academy of Sciences of the United States of America, Vol 109, Issue 21, pp. 8298-303.

Vallières, Cindy, Fisher, Nicholas, Antoine, Thomas, Al-Helal, Mohammed, Stocks, Paul A., Berry, Neil G, Lawrenson, Alexandre S, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, O'Neill, Paul M, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Meunier, Brigitte (2012) 'HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.'. Antimicrobial Agents and Chemotherapy, Vol 56, Issue 7, pp. 3739-47.

Sharma, Raman, Lawrenson, Alexandre S, Fisher, Nicholas, Warman, Ashley, Shone, Alison, Hill, Alasdair, Mbekeani, Alison, Pidathala, Chandrakala, Amewu, Richard K, Leung, Suet, Gibbons, Peter, Hong, David W, Stocks, Paul A., Nixon, Gemma L, Chadwick, James, Shearer, Joanne, Gowers, Ian, Cronk, David, Parel, Serge P, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Berry, Neil G (2012) 'Identification of novel antimalarial chemotypes via chemoinformatic compound selection methods for a high-throughput screening program against the novel malarial target, PfNDH2: increasing hit rate via virtual screening methods.'. Journal of medicinal chemistry, Vol 55, Issue 7, pp. 3144-54.

Fisher, Nicholas, Abd Majid, Roslaini, Antoine, Thomas, Al-Helal, Mohammed, Warman, Ashley, Johnson, David, Lawrenson, Alexandre S., Ranson, Hilary ORCID: https://orcid.org/0000-0003-2332-8247, O'Neill, Paul M, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2012) 'Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression.'. The Journal of Biological Chemistry, Vol 287, Issue 13, pp. 9731-9741.

Pidathala, Chandrakala, Amewu, Richard, Pacorel, Bénédicte, Nixon, Gemma L, Gibbons, Peter, Hong, W David, Leung, Suet C, Berry, Neil G, Sharma, Raman, Stocks, Paul A., Srivastava, Abhishek, Shone, Alison, Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Hill, Alasdair, Fisher, Nicholas, Warman, Ashley, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2012) 'Identification, design and biological evaluation of bisaryl quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).'. Journal of medicinal chemistry, Vol 55, Issue 5, pp. 1831-1843.

Leung, Suet C, Gibbons, Peter, Amewu, Richard, Nixon, Gemma L, Pidathala, Chandrakala, Hong, W David, Pacorel, Bénédicte, Berry, Neil G, Sharma, Raman, Stocks, Paul A., Srivastava, Abhishek, Shone, Alison, Charoensutthivarakul, Sitthivut, Taylor, Lee, Berger, Olivier, Mbekeani, Alison, Hill, Alasdair, Fisher, Nicholas, Warman, Ashley, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2012) 'Identification, design and biological evaluation of heterocyclic quinolones targeting Plasmodium falciparum type II NADH:quinone oxidoreductase (PfNDH2).'. Journal of medicinal chemistry, Vol 55, Issue 5, pp. 1844-1857.

Cowley, Robin, Leung, Suet, Fisher, Nicholas, Al-Helal, Mohammed, Berry, Neil G., Lawrenson, Alexandre S., Sharma, Raman, Shone, Alison, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and O′Neill, Paul M. (2012) 'The development of quinolone esters as novel antimalarial agents targeting the Plasmodium falciparum bc1 protein complex'. MedChemComm, Vol 3, Issue 1, pp. 39-44.

Salcedo, Enrique, Ochong, Edwin, Beveridge, Susan, Johnson, David, Nzila, Alexis, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Stocks, Paul A., O'Neill, Paul M, Krishna, Sanjeev, Bray, Patrick and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2011) 'The molecular basis of folate salvage in Plasmodium falciparum: Characterization of two folate transporters.'. The Journal of Biological Chemistry, Vol 286, Issue 52, pp. 44659-44668.

Berger, Olivier, Kaniti, Archana, Ba, Christophe Tran van, Vial, Henri, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick and O'Neill, Paul M (2011) 'Synthesis and Antimalarial Activities of a Diverse Set of Ariazole-Containing Furamidine Analogues.'. ChemMedChem, Vol 6, Issue 11, pp. 2094-2108.

Rodrigues, Tiago, Moreira, Rui, Gut, Jiri, Rosenthal, Philip J, O Neill, Paul M, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Lopes, Francisca, Dos Santos, Daniel J V A and Guedes, Rita C (2011) 'Identification of new antimalarial leads by use of virtual screening against cytochrome bc(1).'. Bioorganic and Medicinal Chemistry, Vol 19, Issue 21, pp. 6302-8.

Gibbons, Peter, Verissimo, Edite, Araujo, Nuna C, Barton, Victoria, Nixon, Gemma L, Amewu, Richard K, Chadwick, James, Stocks, Paul A., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Srivastava, Abhishek, Rosenthal, Philip J, Gut, Jiri, Guedes, Rita C, Moreira, Rui, Sharma, Raman, Berry, Neil, Cristiano, M Lurdes S, Shone, Alison, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M (2010) 'Endoperoxide carbonyl falcipain 2/3 inhibitor hybrids: toward combination chemotherapy of malaria through a single chemical entity.'. Journal of medicinal chemistry, Vol 53, Issue 22, pp. 8202-6.

Lucumi, Edinson, Darling, Claire, Jo, Hyunil, Napper, Andrew D., Chandramohanadas, Rajesh, Fisher, Nicholas, Shone, Alison, Jing, Huiyan, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, DeGrado, William F, Diamond, Scott L and Greenbaum, Doron C (2010) 'Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay.'. Antimicrobial Agents and Chemotherapy, Vol 54, Issue 9, pp. 3597-3604.

Barton, Victoria, Fisher, Nicholas, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and O'Neill, Paul M. (2010) 'Inhibiting Plasmodium cytochrome bc1: a complex issue.'. Current Opinion in Chemical Biology, Vol 14, Issue 4, pp. 440-446.

Henry, Roselani I, Cobbold, Simon A., Allen, Richard J. W., Khan, Asif, Hayward, Rhys, Lehane, Adele M., Bray, Patrick, Howitt, Susan M., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Saliba, Kevin J. and Kirk, Kiaran (2010) 'An acid-loading chloride transport pathway in the intraerythrocytic malaria parasite, Plasmodium falciparum.'. The Journal of Biological Chemistry, Vol 285, Issue 24, pp. 18615-18626.

Hughes, Katie R, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Craig, Alister ORCID: https://orcid.org/0000-0003-0914-6164 (2010) 'Continued cytoadherence of Plasmodium falciparum infected red blood cells after antimalarial treatment.'. Molecular and biochemical parasitology, Vol 169, Issue 2, pp. 71-78.

Kongkathip, Ngampong, Pradidphol, Narathip, Hasitapan, Komkrit, Grigg, Ronald, Kao, Wei-Chun, Hunte, Carola, Fisher, Nicholas, Warman, Ashley, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Kongsaeree, Palangpon, Chuawong, Pitak and Kongkathip, Boonsong (2010) 'Transforming rhinacanthin analogues from potent anticancer agents into potent antimalarial agents.'. Journal of medicinal chemistry, Vol 53, Issue 3, pp. 1211-1221.

O'Neill, Paul M., Shone, Alison, Stanford, Deborah, Nixon, Gemma, Asadollahy, Eghbaleh, Park, B. Kevin, Maggs, James L., Roberts, Phil, Stocks, Paul A., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick, Davies, Jill, Berry, Neil, Hall, Charlotte, Rimmer, Karen, Winstanley, Peter A., Hindley, Stephen, Bambal, Ramesh B., Davis, Charles B., Bates, Martin, Gresham, Stephanie L., Brigandi, Richard A., Gomez-de-las-Heras, Federico M., Gargallo, Domingo V., Parapini, Silvia, Vivas, Livia, Lander, Hollie, Taramelli, Donatella and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2009) 'Synthesis, Antimalarial Activity, and Preclinical Pharmacology of a Novel Series of 4′-Fluoro and 4′-Chloro Analogues of Amodiaquine. Identification of a Suitable “Back-Up” Compound for N-tert-Butyl Isoquine'. Journal of Medicinal Chemistry, Vol 52, Issue 7, pp. 1828-1844.

Lian, L. Y., Al-Helal, Mohammed, Roslaini, A. M., Fisher, Nicholas, Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2009) 'Glycerol: An unexpected major metabolite of energy metabolism by the human malaria parasite'. Malaria Journal, Vol 8, p. 38.

O'Neill, Paul M., Park, B. Kevin, Shone, Alison, Maggs, James L., Roberts, Phillip, Stocks, Paul A., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick, Gibbons, Peter, Berry, Neil, Winstanley, Peter A., Mukhtar, Amira, Bonar-Law, Richard, Hindley, Stephen, Bambal, Ramesh B., Davis, Charles B., Bates, Martin, Hart, Timothy K., Gresham, Stephanie L., Lawrence, Ron M., Brigandi, Richard A., Gomez-delas-Heras, Federico M., Gargallo, Domingo V. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2009) 'Candidate Selection and Preclinical Evaluation of N-tert-Butyl Isoquine (GSK369796), An Affordable and Effective 4-Aminoquinoline Antimalarial for the 21st Century'. Journal of Medicinal Chemistry, Vol 52, Issue 5, pp. 1408-1415.

Fisher, Nicholas, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2008) 'Modelling, cloning and expression of the P.falciparum NADH dehydrogenase'. Biochimica Et Biophysica Acta-Bioenergetics, Vol 1777, S38-S38.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fisher, Nicholas, Berry, N., Stocks, Paul A., Meunier, B., Williams, D. P., Bonar-Law, R., Bray, Patrick, Owen, A., O'Neill, P. M. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Acridinediones: Selective and potent inhibitors of the malaria parasite mitochondrial bc(1) complex'. Molecular Pharmacology, Vol 73, Issue 5, pp. 1347-1355.

Quashie, N. B., Dorin-Semblat, D., Bray, Patrick, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Doerig, C., Ranford-Cartwright, L. C. and de Koning, H. P. (2008) 'A comprehensive model of purine uptake by the malaria parasite Plasmodium falciparum: identification of four purine transport activities in intraerythrocytic parasites'. Biochemical Journal, Vol 411, Issue 2, pp. 287-295.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fisher, Nicholas, Berry, N., Stocks, Paul A., Meunier, B., Bray, Patrick, Owen, A., O'Neill, P. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2008) 'Acridinediones: a new class of potent inhibitors selective against the mitochondrial bc1 complex of the malaria parasite Plasmodium falciparum.'. International Journal for Parasitology, Vol 38, Issue Supplement 1, S41-S41.

Fisher, Nicholas, Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2007) 'Malaria-parasite mitochondrial dehydrogenases as drug targets: too early to write the obituary'. Trends in Parasitology, Vol 24, Issue 1, pp. 9-10.

Stocks, Paul A., Bray, Patrick, Barton, V. E., Al-Helal, Mohammed, Jones, M., Araujo, N. C., Gibbons, P., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Hughes, Ruth, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Davies, Jill, Amewu, R., Mercer, A. E., Ellis, G. and O'Neill, P. M. (2007) 'Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs'. Angewandte Chemie-International Edition, Vol 46, Issue 33, pp. 6278-6283.

Fisher, Nicholas, Bray, Patrick, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2007) 'The malaria parasite type IINADH : quinone oxidoreductase: an alternative enzyme for an alternative lifestyle'. Trends in Parasitology, Vol 23, Issue 7, pp. 305-310.

Harris, K. M., Goldberg, B., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Lloyd, D. (2007) 'Trichomonas vaginalis and Giardia intestinalis produce nitric oxide.'. Journal of Eukaryotic Microbiology, Vol 54, Issue 2, 41s-42s.

Harris, K. M., Goldberg, B., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Lloyd, D. (2006) 'Trichomonas vaginalis and Giardia intestinalis produce nitric oxide and display NO-synthase activity'. Journal of Eukaryotic Microbiology, Vol 53, Issue S1, S182-S183.

Richier, E., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Wein, S., Boudou, F., Bray, Patrick, Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192, Precigout, E., Calas, M., Dubremetz, J. F. and Vial, H. J. (2006) 'Potent antihematozoan activity of novel bisthiazolium drug T16: Evidence for inhibition of phosphatidylcholine metabolism in erythrocytes infected with Babesia and Plasmodium spp.'. Antimicrobial Agents and Chemotherapy, Vol 50, Issue 10, pp. 3381-3388.

Bray, Patrick, Mungthin, M., Hastings, Ian ORCID: https://orcid.org/0000-0002-1332-742X, Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Saidu, D. K., Lakshmanan, V., Johnson, David, Hughes, Ruth, Stocks, Paul A., O'Neill, P. M., Fidock, D. A., Warhurst, D. C. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'PfCRT and the trans-vacuolar proton electrochemical gradient: regulating the access of chloroquine to ferriprotoporphyrin IX'. Molecular Microbiology, Vol 62, Issue 1, pp. 238-251.

O'Neill, P. M., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192, Berry, N. G., Jeyadevan, J. P., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Asadollaly, E., Park, B. K. and Bray, Patrick (2006) 'A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs'. Current Topics in Medicinal Chemistry, Vol 6, Issue 5, pp. 479-507.

Edwards, Geoffrey and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2006) 'Resisting resistance: dealing with the irrepressible problem of malaria'. British Journal of Clinical Pharmacology, Vol 61, Issue 6, pp. 690-693.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Viriyavejakul, P., O'Neill, P. M., Bray, Patrick and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2006) 'Functional characterization and target validation of alternative complex I of Plasmodium falciparum mitochondria'. Antimicrobial Agents and Chemotherapy, Vol 50, Issue 5, pp. 1841-1851.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Fidock, D. A., Bray, Patrick and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Mutations conferring drug resistance in malaria parasite drug transporters Pgh1 and PfCRT do not affect steady-state vacuolar Ca2+ [Letter to the Editor]'. Antimicrobial Agents and Chemotherapy, Vol 49, Issue 11, pp. 4807-4808.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, O'Neill, P. M., Bray, Patrick and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2005) 'Current drug development portfolio for antimalarial therapies'. Current Opinion in Pharmacology, Vol 5, Issue 5, pp. 473-478.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Bray, Patrick (2005) 'Malaria parasite transporters as a drug-delivery strategy'. Trends in Parasitology, Vol 21, Issue 7, pp. 299-301.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Pasini, E. M., Hughes, Ruth, De Koning, H. P., Vial, H. J., O'Neill, P. M., Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Bray, Patrick (2004) 'Characterization of the choline carrier of Plasmodium falciparum: a route for the selective delivery of novel antimalarial chugs'. Blood, Vol 104, Issue 10, pp. 3372-3377.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, O'Neill, Paul M., Nzila, Alexis, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Bray, Patrick (2003) 'Antimalarial chemotherapy: young guns or back to the future?'. Trends in Parasitology, Vol 19, Issue 11, pp. 479-487.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Richier, E., Bray, Patrick, Calas, M., Vial, H. and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2003) 'Heme binding contributes to antimalarial activity of bis-quaternary ammoniums'. Antimicrobial Agents and Chemotherapy, Vol 47, Issue 8, pp. 2584-2589.

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick, Spiller, D. G., White, M. R. H. and Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 (2003) 'The digestive food vacuole of the malaria parasite is a dynamic intracellular Ca2+ store'. Journal of Biological Chemistry, Vol 278, Issue 30, pp. 27910-27915.

Book Section

Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595, Bray, Patrick and Ward, Steve ORCID: https://orcid.org/0000-0003-2331-3192 (2017) 'Mechanisms of Antimalarial Drug Resistance' in: Meyers, Douglas L., (ed) Antimicrobial Drug Resistance, Mechanisms of Drug Resistance, Volume 1, Cham, Switzerland, Springer, pp. 629-647.

Fisher, Nicholas, Warman, Ashley, Ward, Stephen ORCID: https://orcid.org/0000-0003-2331-3192 and Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 (2010) 'Chapter 17 Type II NADH: Quinone Oxidoreductases of Plasmodium Falciparum and Mycobacterium Tuberculosis. Kinetic and High-Throughput Assays' in: Allison, W. S. and Scheffler, I. E., (eds) Methods in Enzymology, 456, San Diego, Calif., Academic Press, pp. 303-320.

Conference or Workshop Item

Donnellan, Samantha, Ruggiero, A., Pennington, Shaun ORCID: https://orcid.org/0000-0002-7160-6275, Thomas, J., Pollakis, G., Biagini, Giancarlo ORCID: https://orcid.org/0000-0001-6356-6595 and Paxton, W. (2020) 'OA-37-733-24 An in vitro intracellular Mycobacterium tuberculosis and HIV-1 co-infection model suitable for imaging-based platforms' in 51st World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease, Online, 20 -24 October 2020.