LSTM Home > LSTM Research > LSTM Online Archive

Co-existing sickle cell anaemia and inflammatory bowel disease: case report and review of the literature

Adepoju, A A, Akere, A, Ogun, G O, Ogunbosi, B O, Asinobi, A O, Bello, O, Orimadegun, A E, Allen, Stephen ORCID: and Akinyinka, O O (2021) 'Co-existing sickle cell anaemia and inflammatory bowel disease: case report and review of the literature'. Paediatrics and international child health, Vol 42, Issue 1, pp. 29-35.

[img] Text
PCH2475R4-180521 - Steve Allen.docx - Accepted Version

Download (87kB)
[img] Text
Figure 1.docx - Supplemental Material

Download (672kB)
[img] Text
Figure 2.docx - Supplemental Material

Download (1MB)
[img] Text
Figure 3.docx - Supplemental Material

Download (1MB)


Sickle cell anaemia (SCA) is a chronic haemolytic anaemia associated with vaso-occlusive painful crises which may affect several systems including the gastro-intestinal system, resulting in abdominal pain. The concurrence of inflammatory bowel disease and haemoglobinopathy is rare. No previously reported concurrent cases of both SCA and ulcerative colitis (UC) in sub-Saharan Africa were found in the literature. A 16-year-old girl with concurrent SCA and UC is presented. She was admitted to University College Hospital, Ibadan with a 1-year history of recurrent peri-umbilical pain and bloody stools. These symptoms were mainly attributed to SCA at the referring hospital, and she was managed for chronic tropical diarrhoea without a remarkable clinical response. This case illustrates the concurrent presentation of SCA and ulcerative colitis which led to the missed and delayed diagnosis of ulcerative colitis.

Item Type: Article
Subjects: WH Hemic and Lymphatic Systems > Hematologic Diseases. Immunologic Factors. Blood Banks > WH 170 Hemolytic anemia (e.g., Sickle cell anemia)
WI Digestive System > WI 100 General works
WI Digestive System > WI 140 Diseases (General)
Faculty: Department: Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):
Depositing User: Julie Franco
Date Deposited: 08 Sep 2021 11:47
Last Modified: 02 Feb 2023 08:51


View details

Actions (login required)

Edit Item Edit Item