Co-existing sickle cell anaemia and inflammatory bowel disease: case report and review of the literature

Adepoju, A A, Akere, A, Ogun, G O, Ogunbosi, B O, Asinobi, A O, Bello, O, Orimadegun, A E, Allen, Stephen ORCID: https://orcid.org/0000-0001-6675-249X and Akinyinka, O O (2021) 'Co-existing sickle cell anaemia and inflammatory bowel disease: case report and review of the literature'. Paediatrics and international child health, Vol 42, Issue 1, pp. 29-35.

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Abstract

Sickle cell anaemia (SCA) is a chronic haemolytic anaemia associated with vaso-occlusive painful crises which may affect several systems including the gastro-intestinal system, resulting in abdominal pain. The concurrence of inflammatory bowel disease and haemoglobinopathy is rare. No previously reported concurrent cases of both SCA and ulcerative colitis (UC) in sub-Saharan Africa were found in the literature. A 16-year-old girl with concurrent SCA and UC is presented. She was admitted to University College Hospital, Ibadan with a 1-year history of recurrent peri-umbilical pain and bloody stools. These symptoms were mainly attributed to SCA at the referring hospital, and she was managed for chronic tropical diarrhoea without a remarkable clinical response. This case illustrates the concurrent presentation of SCA and ulcerative colitis which led to the missed and delayed diagnosis of ulcerative colitis.

Item Type:	Article
Subjects:	WH Hemic and Lymphatic Systems > Hematologic Diseases. Immunologic Factors. Blood Banks > WH 170 Hemolytic anemia (e.g., Sickle cell anemia) WI Digestive System > WI 100 General works WI Digestive System > WI 140 Diseases (General)
Faculty: Department:	Clinical Sciences & International Health > Clinical Sciences Department
Digital Object Identifer (DOI):	https://doi.org/10.1080/20469047.2021.1936393
Depositing User:	Julie Franco
Date Deposited:	08 Sep 2021 11:47
Last Modified:	02 Feb 2023 08:51
URI:	https://archive.lstmed.ac.uk/id/eprint/18869

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